Parsitological and histo-pathlogical studies on schisto-somiasis mansoni infect5ed mice and treatment with praziqutel andor oltipraz

الملخص EN

Thirty five (70%) of 51 Carangoides bajad were naturally infected with Ani-sakis simplex during the period from September 2007 to January 2008.

The fish were collected from eastern south coast of the Red Sea at Hurgada.

The mor¬phological and ultrastructures of Anisakis larvae and adults, and the induced lesions in the fish (intermediate host), five puppies (final host) were orally giv¬en infected fish.

The body of the larvae is gradually tapering towards the anterior part.

It is covered by striated ornamentation longitudinally and horizontally, except the anterior region which is smooth.

The morphological and ultrastrutural examina¬tions of the anterior body end of larvae showed a prominent boring tooth, 3 pairs of lips inconspicuous and an excretory ventral pore between the rudimen¬tary subventral lips.

The anal end showed a distinct mucron and a slit-shaped anus.

The pathological studies revealed encapsulated larvae with concentrical fibrous connective tissue infiltrated, with macrophages and lymphocytes on the surface of liver, spleen and peritoneum of the infected fish.

The macrophages aggregated together to form the denser part of the capsule, and invaded the ad¬jacent parenchymal tissue.

The hepatocytes, under the affected capsule were necrotic and invaded by melanomacrophages