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Evaluation of Epithelial Integrity with Various Transepithelial Corneal Cross-Linking Protocols for Treatment of Keratoconus
المؤلفون المشاركون
Taneri, Suphi
Oehler, Saskia
Lytle, Grace
Dick, H. Burkhard
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-12
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Purpose.
Corneal collagen cross-linking (CXL) has been demonstrated to stiffen cornea and halt progression of ectasia.
The original protocol requires debridement of central corneal epithelium to facilitate diffusion of a riboflavin solution to stroma.
Recently, transepithelial CXL has been proposed to reduce risk of complications associated with epithelial removal.
Aim of the study is to evaluate the impact of various transepithelial riboflavin delivery protocols on corneal epithelium in regard to pain and epithelial integrity in the early postoperative period.
Methods.
One hundred and sixty six eyes of 104 subjects affected by progressive keratoconus underwent transepithelial CXL using 6 different riboflavin application protocols.
Postoperatively, epithelial integrity was evaluated at slit lamp and patients were queried regarding their ocular pain level.
Results.
One eye had a corneal infection associated with an epithelial defect.
No other adverse event including endothelial decompensation or endothelial damage was observed, except for epithelial damages.
Incidence of epithelial defects varied from 0 to 63%.
Incidence of reported pain varied from 0 to 83%.
Conclusion.
Different transepithelial cross-linking protocols have varying impacts on epithelial integrity.
At present, it seems impossible to have sufficient riboflavin penetration without any epithelial disruption.
A compromise between efficacy and epithelial integrity has to be found.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Taneri, Suphi& Oehler, Saskia& Lytle, Grace& Dick, H. Burkhard. 2014. Evaluation of Epithelial Integrity with Various Transepithelial Corneal Cross-Linking Protocols for Treatment of Keratoconus. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1042587
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Taneri, Suphi…[et al.]. Evaluation of Epithelial Integrity with Various Transepithelial Corneal Cross-Linking Protocols for Treatment of Keratoconus. Journal of Ophthalmology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1042587
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Taneri, Suphi& Oehler, Saskia& Lytle, Grace& Dick, H. Burkhard. Evaluation of Epithelial Integrity with Various Transepithelial Corneal Cross-Linking Protocols for Treatment of Keratoconus. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1042587
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1042587
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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