A Cornea Substitute Derived from Fish Scale: 6-Month Followup on Rabbit Model
المؤلفون المشاركون
Yuan, Fei
Wang, Liyan
Lin, Chien-Chen
Chou, Cheng-Hung
Li, Lei
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
A fish scale-derived cornea substitute (Biocornea) is proposed as an alternative for human donor corneal tissue.
We adopt a regenerative medicine approach to design a primary alternative to the use of fish scale for restoring sight by corneal replacement.
Biocornea with corneal multilayer arrangement collagen was implanted to rabbits by pocket implantation.
Our study demonstrated the safety and detailed morphologic and physiologic results from the 6 months of followup of rabbit model.
In the peripheral Biocornea, the collagen fibrils were arranged in reticular fashion.
Slit lamp examination showed that haze and an ulcer were not observed in all groups at 3 months postoperatively while all corneas with Biocornea were clear at both 3 months and 6 months postoperatively.
The interface of Biocornea and stromal tissue were filled successfully and without observable immune cells at postoperative day 180.
Moreover, the Biocornea was not dissolved and degenerated but remained transparent and showed no apparent fragmentation.
Our study demonstrated that the Biocornea derived from fish scale as a good substitute had high biocompatibility and support function after a long-term evaluation.
This revealed that the new approach of using Biocornea may yield an ideal artificial cornea substitute for long-term inlay placement.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yuan, Fei& Wang, Liyan& Lin, Chien-Chen& Chou, Cheng-Hung& Li, Lei. 2014. A Cornea Substitute Derived from Fish Scale: 6-Month Followup on Rabbit Model. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042648
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yuan, Fei…[et al.]. A Cornea Substitute Derived from Fish Scale: 6-Month Followup on Rabbit Model. Journal of Ophthalmology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1042648
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yuan, Fei& Wang, Liyan& Lin, Chien-Chen& Chou, Cheng-Hung& Li, Lei. A Cornea Substitute Derived from Fish Scale: 6-Month Followup on Rabbit Model. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042648
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1042648
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر