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Influence of Second-Trimester Ultrasound Markers for Down Syndrome in Pregnant Women of Advanced Maternal Age
المؤلفون المشاركون
Rumi Kataguiri, Mariza
Araujo Júnior, Edward
Nardozza, Luciano Marcondes Machado
Moron, Antonio Fernandes
Bussamra, Luiz Cláudio de Silva
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-25
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The objective of the present study was to evaluate the influence of second-trimester ultrasound markers on the incidence of Down syndrome among pregnant women of advanced maternal age.
This was a retrospective cohort study on 889 singleton pregnancies between the 14th and 30th weeks, with maternal age ≥ 35 years, which would undergo genetic amniocentesis.
The second-trimester ultrasound assessed the following markers: increased nuchal fold thickness, cardiac hyperechogenic focus, mild ventriculomegaly, choroid plexus cysts, uni- or bilateral renal pyelectasis, intestinal hyperechogenicity, single umbilical artery, short femur and humerus length, hand/foot alterations, structural fetal malformation, and congenital heart disease.
To investigate differences between the groups with and without markers, nonparametric tests consisting of the chi-square test or Fisher’s exact test were used.
Moreover, odds ratios with their respective 95% confidence intervals were calculated.
Out of the 889 pregnant women, 131 (17.3%) presented markers and 758 (82.7%) did not present markers on the second-trimester ultrasound.
Increased nuchal fold ( P < 0.001 ) and structural malformation ( P < 0.001 ) were the markers most associated with Down syndrome.
The presence of one marker increased the relative risk 10.5-fold, while the presence of two or more markers increased the risk 13.5-fold.
The presence of markers on the second-trimester ultrasound, especially thickened nuchal fold and structural malformation, increased the risk of Down syndrome among pregnant women with advanced maternal age.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rumi Kataguiri, Mariza& Araujo Júnior, Edward& Bussamra, Luiz Cláudio de Silva& Nardozza, Luciano Marcondes Machado& Moron, Antonio Fernandes. 2014. Influence of Second-Trimester Ultrasound Markers for Down Syndrome in Pregnant Women of Advanced Maternal Age. Journal of Pregnancy،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042733
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rumi Kataguiri, Mariza…[et al.]. Influence of Second-Trimester Ultrasound Markers for Down Syndrome in Pregnant Women of Advanced Maternal Age. Journal of Pregnancy No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1042733
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rumi Kataguiri, Mariza& Araujo Júnior, Edward& Bussamra, Luiz Cláudio de Silva& Nardozza, Luciano Marcondes Machado& Moron, Antonio Fernandes. Influence of Second-Trimester Ultrasound Markers for Down Syndrome in Pregnant Women of Advanced Maternal Age. Journal of Pregnancy. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042733
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1042733
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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