Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment
المؤلفون المشاركون
Mukaida, Naofumi
Sasaki, So-ichiro
Baba, Tomohisa
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-22
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Chemokines were initially identified as bioactive substances, which control the trafficking of inflammatory cells including granulocytes and monocytes/macrophages.
Moreover, chemokines have profound impacts on other types of cells associated with inflammatory responses, such as endothelial cells and fibroblasts.
These observations would implicate chemokines as master regulators in various inflammatory responses.
Subsequent studies have further revealed that chemokines can regulate the movement of a wide variety of immune cells including lymphocytes, natural killer cells, and dendritic cells in both physiological and pathological conditions.
These features endow chemokines with crucial roles in immune responses.
Furthermore, increasing evidence points to the vital effects of several chemokines on the proliferative and invasive properties of cancer cells.
It is widely acknowledged that cancer develops and progresses to invade and metastasize in continuous interaction with noncancerous cells present in cancer tissues, such as macrophages, lymphocytes, fibroblasts, and endothelial cells.
The capacity of chemokines to regulate both cancerous and noncancerous cells highlights their crucial roles in cancer development and progression.
Here, we will discuss the roles of chemokines in carcinogenesis and the possibility of chemokine targeting therapy for the treatment of cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mukaida, Naofumi& Sasaki, So-ichiro& Baba, Tomohisa. 2014. Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1043353
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mukaida, Naofumi…[et al.]. Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment. Mediators of Inflammation No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-1043353
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mukaida, Naofumi& Sasaki, So-ichiro& Baba, Tomohisa. Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1043353
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043353
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر