Preventive Effects of Chitosan Coacervate Whey Protein on Body Composition and Immunometabolic Aspect in Obese Mice
المؤلفون المشاركون
Souza, Gabriel I. H.
Rodrigues, Bruno
Santana, Aline Alves
Santamarina, Aline Boveto
Laquila, Rachel de
Esposito, Elisa
Oller do Nascimento, Claudia Maria da Penha
Lira, Fabio Santos
Oyama, Lila Missae
Ribeiro, Eliane B.
Moreno, Mayara Franzoi
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-17
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Functional foods containing bioactive compounds of whey may play an important role in prevention and treatment of obesity.
The aim of this study was to investigate the prospects of the biotechnological process of coacervation of whey proteins (CWP) in chitosan and test its antiobesogenic potential.
Methods.
CWP (100 mg·kg·day) was administered in mice with diet-induced obesity for 8 weeks.
The animals were divided into four groups: control normocaloric diet gavage with water (C) or coacervate (C-CWP), and high fat diet gavage with water (HF) or coacervate (HF-CWP).
Results.
HF-CWP reduced weight gain and serum lipid fractions and displayed reduced adiposity and insulin.
Adiponectin was significantly higher in HF-CWP group when compared to the HF.
The level of LPS in HF-W group was significantly higher when compared to HF-CWP.
The IL-10 showed an inverse correlation between the levels of insulin and glucose in the mesenteric adipose tissue in the HF-CWP group.
CWP promoted an increase in both phosphorylation AMPK and the amount of ATGL in the mesenteric adipose tissue in HF-CWP group.
Conclusion.
CWP was able to modulate effects, possibly due to its high biological value of proteins.
We observed a protective effect against obesity and improved the inflammatory milieu of white adipose tissue.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Souza, Gabriel I. H.& Santamarina, Aline Boveto& Santana, Aline Alves& Lira, Fabio Santos& Laquila, Rachel de& Moreno, Mayara Franzoi…[et al.]. 2014. Preventive Effects of Chitosan Coacervate Whey Protein on Body Composition and Immunometabolic Aspect in Obese Mice. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1043416
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Souza, Gabriel I. H.…[et al.]. Preventive Effects of Chitosan Coacervate Whey Protein on Body Composition and Immunometabolic Aspect in Obese Mice. Mediators of Inflammation No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-1043416
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Souza, Gabriel I. H.& Santamarina, Aline Boveto& Santana, Aline Alves& Lira, Fabio Santos& Laquila, Rachel de& Moreno, Mayara Franzoi…[et al.]. Preventive Effects of Chitosan Coacervate Whey Protein on Body Composition and Immunometabolic Aspect in Obese Mice. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1043416
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043416
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر