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Intestinal Parasites Coinfection Does Not Alter Plasma Cytokines Profile Elicited in Acute Malaria in Subjects from Endemic Area of Brazil
المؤلفون المشاركون
Sánchez-Arcila, Juan Camilo
Perce-da-Silva, Daiana de Souza
Vasconcelos, Mariana Pinheiro Alves
Rodrigues-da-Silva, Rodrigo Nunes
Pereira, Virginia Araujo
Aprígio, Cesarino Junior Lima
Lima, Cleoni Alves Mendes
Fonseca, Bruna de Paula Fonseca e
Banic, Dalma Maria
Lima-Junior, Josué da Costa
Oliveira-Ferreira, Joseli
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-16
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
In Brazil, malaria is prevalent in the Amazon region and these regions coincide with high prevalence of intestinal parasites but few studies explore the interaction between malaria and other parasites.
Therefore, the present study evaluates changes in cytokine, chemokine, C-reactive protein, and nitric oxide (NO) concentrations in 264 individuals, comparing plasma from infected individuals with concurrent malaria and intestinal parasites to individuals with either malaria infection alone and uninfected.
In the studied population 24% of the individuals were infected with Plasmodium and 18% coinfected with intestinal parasites.
Protozoan parasites comprised the bulk of the intestinal parasites infections and subjects infected with intestinal parasites were more likely to have malaria.
The use of principal component analysis and cluster analysis associated increased levels of IL-6, TNF-α, IL-10, and CRP and low levels of IL-17A predominantly with individuals with malaria alone and coinfected individuals.
In contrast, low levels of almost all inflammatory mediators were associated predominantly with individuals uninfected while increased levels of IL-17A were associated predominantly with individuals with intestinal parasites only.
In conclusion, our data suggest that, in our population, the infection with intestinal parasites (mainly protozoan) does not modify the pattern of cytokine production in individuals infected with P.
falciparum and P.
vivax.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sánchez-Arcila, Juan Camilo& Perce-da-Silva, Daiana de Souza& Vasconcelos, Mariana Pinheiro Alves& Rodrigues-da-Silva, Rodrigo Nunes& Pereira, Virginia Araujo& Aprígio, Cesarino Junior Lima…[et al.]. 2014. Intestinal Parasites Coinfection Does Not Alter Plasma Cytokines Profile Elicited in Acute Malaria in Subjects from Endemic Area of Brazil. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1043849
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sánchez-Arcila, Juan Camilo…[et al.]. Intestinal Parasites Coinfection Does Not Alter Plasma Cytokines Profile Elicited in Acute Malaria in Subjects from Endemic Area of Brazil. Mediators of Inflammation No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1043849
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sánchez-Arcila, Juan Camilo& Perce-da-Silva, Daiana de Souza& Vasconcelos, Mariana Pinheiro Alves& Rodrigues-da-Silva, Rodrigo Nunes& Pereira, Virginia Araujo& Aprígio, Cesarino Junior Lima…[et al.]. Intestinal Parasites Coinfection Does Not Alter Plasma Cytokines Profile Elicited in Acute Malaria in Subjects from Endemic Area of Brazil. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1043849
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043849
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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