Involvement of Thalamus in Initiation of Epileptic Seizures Induced by Pilocarpine in Mice
المؤلفون المشاركون
Liang, Pei-Ji
Zhang, Pu-Ming
Lu, Qin-Chi
Li, Yong-Hua
Li, Jia-Jia
Gong, Hai-Qing
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-20
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Studies have suggested that thalamus is involved in temporal lobe epilepsy, but the role of thalamus is still unclear.
We obtained local filed potentials (LFPs) and single-unit activities from CA1 of hippocampus and parafascicular nucleus of thalamus during the development of epileptic seizures induced by pilocarpine in mice.
Two measures, redundancy and directionality index, were used to analyze the electrophysiological characters of neuronal activities and the information flow between thalamus and hippocampus.
We found that LFPs became more regular during the seizure in both hippocampus and thalamus, and in some cases LFPs showed a transient disorder at seizure onset.
The variation tendency of the peak values of cross-correlation function between neurons matched the variation tendency of the redundancy of LFPs.
The information tended to flow from thalamus to hippocampus during seizure initiation period no matter what the information flow direction was before the seizure.
In some cases the information flow was symmetrically bidirectional, but none was found in which the information flowed from hippocampus to thalamus during the seizure initiation period.
In addition, inactivation of thalamus by tetrodotoxin (TTX) resulted in a suppression of seizures.
These results suggest that thalamus may play an important role in the initiation of epileptic seizures.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Yong-Hua& Li, Jia-Jia& Lu, Qin-Chi& Gong, Hai-Qing& Liang, Pei-Ji& Zhang, Pu-Ming. 2014. Involvement of Thalamus in Initiation of Epileptic Seizures Induced by Pilocarpine in Mice. Neural Plasticity،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1046733
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Yong-Hua…[et al.]. Involvement of Thalamus in Initiation of Epileptic Seizures Induced by Pilocarpine in Mice. Neural Plasticity No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-1046733
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Yong-Hua& Li, Jia-Jia& Lu, Qin-Chi& Gong, Hai-Qing& Liang, Pei-Ji& Zhang, Pu-Ming. Involvement of Thalamus in Initiation of Epileptic Seizures Induced by Pilocarpine in Mice. Neural Plasticity. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1046733
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1046733
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر