Oxidative Stress Is Predominant in Female but Not in Male Patients with Autoimmune Thrombocytopenia
المؤلفون المشاركون
Kamhieh-Milz, Julian
Salama, Abdulgabar
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-06
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
As the involvement of oxidative stress (OS) in autoimmune thrombocytopenia (AITP) has been reported, a fast and rapid test for the reliable measurement of OS and antioxidant capacities (AOCs) might be a useful tool in extending current diagnostic possibilities.
The free oxygen radical test (FORT) and free oxygen radical defence (FORD) assay (Callegari, Italy) are easy to perform and reliable, with results available within 15 minutes.
Thirty-seven AITP patients and 37 matched healthy individuals were included in this study.
All participants responded to a standard questionnaire provided by these assays.
Female patients with AITP were observed to demonstrate significantly higher OS in comparison to female controls ( P = 0.0027 ) and male AITP patients ( P = 0.0018 ).
The AOCs were not reduced in patients with AITP ( P = 0.7648 ).
Correlation of OS with platelet count identified a weak positive correlation ( P = 0.0327 , Spearman R = 0.4672 ).
The questionnaire revealed that ITP patients in comparison to healthy controls are more stressed, feel exhausted and fatigued, and eat a healthier diet.
In conclusion, OS is predominant in female but not in male patients with AITP suggesting gender-specific differences in the pathomechanisms of AITP.
Identification of patients with high levels of OS might be beneficial in the management of AITP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kamhieh-Milz, Julian& Salama, Abdulgabar. 2014. Oxidative Stress Is Predominant in Female but Not in Male Patients with Autoimmune Thrombocytopenia. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1047096
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kamhieh-Milz, Julian& Salama, Abdulgabar. Oxidative Stress Is Predominant in Female but Not in Male Patients with Autoimmune Thrombocytopenia. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1047096
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kamhieh-Milz, Julian& Salama, Abdulgabar. Oxidative Stress Is Predominant in Female but Not in Male Patients with Autoimmune Thrombocytopenia. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1047096
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1047096
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر