Lipid and Protein Oxidation in Newborn Infants after Lutein Administration
المؤلفون المشاركون
Buonocore, Giuseppe
Tei, M.
Longini, M.
Santacroce, A.
Turrisi, G.
Proietti, F.
Felici, C.
Picardi, A.
Bazzini, F.
Vasarri, P.
Perrone, Serafina
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-11
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives.
To test the hypothesis that neonatal supplementation with lutein in the first hours of life reduces neonatal oxidative stress (OS) in the immediate postpartum period.
Methods.
A randomized controlled, double-blinded clinical trial was conducted among 150 newborns divided into control group, not supplemented (n=47), and test group, supplemented with lutein on the first day postpartum (n=103).
Blood Samples were collected at birth from cord and at 48 hrs postpartum while routine neonatal metabolic screenings were taking place.
Total hydroperoxide (TH), advanced oxidation protein products (AOPP), and biological antioxidant potential (BAP) were measured by spectrophotometry and data were analyzed by Wilcoxon rank sum test and by multivariate logistic regression analysis.
Results.
Before lutein supplementation, the mean blood concentrations of AOPP, TH, and BAP were 36.10 umol/L, 156.75 mmol/H2O2, and 2361.04 umol/L in the test group.
After lutein supplementation, significantly higher BAP increment (0.17 ± 0.22 versus 0.06 versus ± 0.46) and lower TH increment (0.46 ± 0.54 versus 0.34 ± 0.52) were observed in the test group compared to controls.
Conclusion.
Neonatal supplementation with lutein in the first hours of life increases BAP and reduces TH in supplemented babies compared to those untreated.
The generation of free radical-induced damage at birth is reduced by lutein.
This trial is registered with ClinicalTrials.gov NCT02068807.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Perrone, Serafina& Tei, M.& Longini, M.& Santacroce, A.& Turrisi, G.& Proietti, F.…[et al.]. 2014. Lipid and Protein Oxidation in Newborn Infants after Lutein Administration. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047128
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Perrone, Serafina…[et al.]. Lipid and Protein Oxidation in Newborn Infants after Lutein Administration. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1047128
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Perrone, Serafina& Tei, M.& Longini, M.& Santacroce, A.& Turrisi, G.& Proietti, F.…[et al.]. Lipid and Protein Oxidation in Newborn Infants after Lutein Administration. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047128
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1047128
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر