The Combined Extract of Purple Waxy Corn and Ginger Prevents Cataractogenesis and Retinopathy in Streptozotocin-Diabetic Rats
المؤلفون المشاركون
Thiraphatthanavong, Paphaphat
Wattanathorn, Jintanaporn
Lertrat, Kamol
Muchimapura, Supaporn
Thukham-mee, Wipawee
Suriharn, Bhalang
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-12-31
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Based on the crucial roles of oxidative stress and aldose reductase on diabetic complications and the protective effect against diabetic eye complication of purple waxy corn and ginger (PWCG) together with the synergistic effect concept, we aimed to determine anticataract and antiretinopathy effects of the combined extract of purple waxy corn and ginger (PWCG).
The streptozotocin diabetics with the blood glucose levels >250 mg·dL−1 were orally given the extract at doses of 50, 100, and 200 mg/kg·BW−1 for 10 weeks.
Then, lens opacity and histopathology of retina were determined.
The changes of MDA together with the activities of SOD, CAT, GPx, and AR in lens were also determined using biochemical assays.
All doses of PWCG decreased lens opacity, MDA, and AR in the lens of diabetic rats.
The elevation of CAT and GPx activities was also observed.
The antiretinopathy property of the combined extract was also confirmed by the increased number of neurons in ganglion cell layer and thickness of total retina and retinal nuclear layer in diabetic rats.
PWCG is the potential functional food to protect against diabetic cataract and retinopathy.
However, further studies concerning toxicity and clinical trial are still essential.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Thiraphatthanavong, Paphaphat& Wattanathorn, Jintanaporn& Muchimapura, Supaporn& Thukham-mee, Wipawee& Lertrat, Kamol& Suriharn, Bhalang. 2014. The Combined Extract of Purple Waxy Corn and Ginger Prevents Cataractogenesis and Retinopathy in Streptozotocin-Diabetic Rats. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1047134
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Thiraphatthanavong, Paphaphat…[et al.]. The Combined Extract of Purple Waxy Corn and Ginger Prevents Cataractogenesis and Retinopathy in Streptozotocin-Diabetic Rats. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1047134
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Thiraphatthanavong, Paphaphat& Wattanathorn, Jintanaporn& Muchimapura, Supaporn& Thukham-mee, Wipawee& Lertrat, Kamol& Suriharn, Bhalang. The Combined Extract of Purple Waxy Corn and Ginger Prevents Cataractogenesis and Retinopathy in Streptozotocin-Diabetic Rats. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1047134
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1047134
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر