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Comorbidity in Adult Bone Sarcoma Patients: A Population-Based Cohort Study
المؤلفون المشاركون
Safwat, Akmal
Keller, Johnny Ø.
Baerentzen, Steen
Aggerholm-Pedersen, Ninna
Maretty-Nielsen, Katja
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-27
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Comorbidity is an important prognostic factor for survival in different cancers; however, neither the prevalence nor the impact of comorbidity has been investigated in bone sarcoma.
Methods.
All adult bone sarcoma patients from western Denmark treated at the Aarhus Sarcoma Centre in the period from 1979 to 2008 were identified through a validated population-based database.
Charlson Comorbidity Index scores were computed, using discharge diagnoses from the Danish National Patient Registry.
Survival was assessed as overall and disease-specific mortality.
The impact of comorbidity was examined as rates according to the level of comorbidity as well as uni- and multivariately using proportional hazard models.
Results.
A total of 453 patients were identified.
The overall prevalence of comorbidity was 19%.
The prevalence increased with age and over the study period.
In patients with Ewing/osteosarcoma, comorbidity was not associated with an increased overall or disease-specific mortality.
However, patients with bone sarcomas other than Ewing/osteosarcoma had increased overall mortality.
Independent prognostic factors for disease-specific survival were age, tumor size, stage at diagnosis, soft tissue involvement, grade, and surgery.
Conclusion.
The prevalence of comorbidity in bone sarcoma patients is low.
Comorbidity impaired survival in patients with non-Ewing/nonosteosarcoma, histology.
This emphasizes the importance of not only treating the sarcoma but also comorbidity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aggerholm-Pedersen, Ninna& Maretty-Nielsen, Katja& Keller, Johnny Ø.& Baerentzen, Steen& Safwat, Akmal. 2014. Comorbidity in Adult Bone Sarcoma Patients: A Population-Based Cohort Study. Complexity،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1047458
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Keller, Johnny Ø.…[et al.]. Comorbidity in Adult Bone Sarcoma Patients: A Population-Based Cohort Study. Complexity Vol. 2014, no. 2014 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1047458
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aggerholm-Pedersen, Ninna& Maretty-Nielsen, Katja& Keller, Johnny Ø.& Baerentzen, Steen& Safwat, Akmal. Comorbidity in Adult Bone Sarcoma Patients: A Population-Based Cohort Study. Complexity. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1047458
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1047458
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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