Adverse Reactions to Antituberculosis Drugs in Iranian Tuberculosis Patients
المؤلفون المشاركون
Farazi, Ali Asghar
Sofian, Masoomeh
Jabbariasl, Mansoureh
Keshavarz, Sara
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-11-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Antituberculosis multidrug regimens have been associated with increased incidence of adverse drug reactions (ADRs).
This study aimed to determine the incidence and associated factors of ADRs due to antituberculosis therapy.
Methods.
This is a retrospective cross-sectional study on tuberculosis patients who were treated in tuberculosis clinics in Markazi province in Iran.
The information contained in the medical files was extracted and entered into the questionnaire.
Data was descriptively analyzed by using statistical package for social sciences (SPSS 18).
Results.
A total of 940 TB patients of 1240 patients’ medical records available in 10 medical offices were included in this study.
Of the 563 ADRs found in this study, 82.4% were considered minor reactions and 17.6% were major reactions.
No death from antituberculosis ADR was observed.
We found that the risk of major ADRs was higher in females ( P value = 0.0241 ), age >50 y ( P value = 0.0223 ), coinfection with HIV ( P value = 0.0323 ), smoking ( P value = 0.002 ), retreatment TB ( P value = 0.0203 ), and comorbidities ( P value = 0.0005 ).
Conclusions.
This study showed that severe side effects of anti-TB drugs are common in patients who have risk factors of ADRs and they should be followed up by close monitoring.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Farazi, Ali Asghar& Sofian, Masoomeh& Jabbariasl, Mansoureh& Keshavarz, Sara. 2014. Adverse Reactions to Antituberculosis Drugs in Iranian Tuberculosis Patients. Tuberculosis Research and Treatment،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1048062
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Farazi, Ali Asghar…[et al.]. Adverse Reactions to Antituberculosis Drugs in Iranian Tuberculosis Patients. Tuberculosis Research and Treatment No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1048062
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Farazi, Ali Asghar& Sofian, Masoomeh& Jabbariasl, Mansoureh& Keshavarz, Sara. Adverse Reactions to Antituberculosis Drugs in Iranian Tuberculosis Patients. Tuberculosis Research and Treatment. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1048062
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1048062
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر