Clinicopathological Characteristics and Outcomes of Chinese Patients with Scanty Immune Deposits Lupus Nephritis: A Large Cohort Study from a Single Center
المؤلفون المشاركون
Zhao, Ming-hui
Li, Qiuyu
Song, Di
Wang, Fengmei
Tan, Ying
Yu, Feng
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-04
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Objective.
To assess clinicopathological characteristics of lupus nephritis patients with scanty immune deposits.
Methods.
The data of patients with scanty immune deposits lupus nephritis were retrospectively analyzed.
Plasma ANCA and complement components were detected.
Results.
Among 316 cases with renal biopsy-proven lupus nephritis, 40 cases were diagnosed as scanty immune deposits.
There were significantly higher value of serum creatinine (P=0.002) and lower hemoglobin level (P=0.009) and higher score of cellular crescents (P=0.015) in scanty immune deposits group compared with immune complex deposits group.
The frequency of positive plasma ANCA was significantly higher in scanty immune deposits group than that in immune complex deposits group (52.5% versus 10.1%, P<0.001).
As for comparisons of plasma complement components, there were significantly higher levels of C1q (P=0.005) and Bb (P=0.02) and lower level of factor H (P=0.003) in scanty immune deposits group.
The ratio of treatment failure was significantly higher in scanty immune deposits group than that in immune deposits group (42.5% versus 19.20%, P=0.001).
The renal outcomes were similar between the two groups.
Conclusions.
Patients with scanty immune deposits lupus nephritis had more severe kidney damage.
ANCA and activation of complement alternative pathway might be involved in the pathogenesis of the disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Qiuyu& Song, Di& Wang, Fengmei& Tan, Ying& Yu, Feng& Zhao, Ming-hui. 2014. Clinicopathological Characteristics and Outcomes of Chinese Patients with Scanty Immune Deposits Lupus Nephritis: A Large Cohort Study from a Single Center. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1048750
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Qiuyu…[et al.]. Clinicopathological Characteristics and Outcomes of Chinese Patients with Scanty Immune Deposits Lupus Nephritis: A Large Cohort Study from a Single Center. The Scientific World Journal No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1048750
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Qiuyu& Song, Di& Wang, Fengmei& Tan, Ying& Yu, Feng& Zhao, Ming-hui. Clinicopathological Characteristics and Outcomes of Chinese Patients with Scanty Immune Deposits Lupus Nephritis: A Large Cohort Study from a Single Center. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1048750
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1048750
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر