The Effect of Local Injections of Bupivacaine Plus Ketamine, Bupivacaine Alone, and Placebo on Reducing Postoperative Anal Fistula Pain: A Randomized Clinical Trial
المؤلفون المشاركون
Kazemeini, Alireza
Rahimi, Mojgan
Mirjafari, Seyedeh Adeleh
Fani, Kamal
Forozeshfard, Mohammad
Matin, Marzieh
Fazeli, Sadegh Mohammad
Ghaderi, Hamid
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-12-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Background and Objective.
This study aimed to compare the effects of different local anesthetic solutions on postoperative pain of anal surgery in adult patients.
Method.
In this randomized double-blind prospective clinical trial, 60 adult patients (18 to 60 years old) with physical status class I and class II that had been brought to a university hospital operating room for fistula anal surgery with spinal anesthesia were selected.
Patients were randomly divided into 4 equal groups according to table of random numbers (created by Random Allocation Software 1).
Group 1 received 3 mL of normal saline, group 2, 1 mL of normal saline plus 2 mL of bupivacaine 0.5%, group 3, 1 mL of ketamine plus 2 mL of bupivacaine 0.5%, and group 4, no infiltration.
Intensity of pain in patients was measured using visual analogue scale (VAS) at 0 (transfer to ward), 2, 6, 12, and 24 hours after surgery.
Time interval to administration of drugs and overall dose of drugs were measured in 4 groups.
Results.
Mean level of pain was the lowest in group 3 at all occasions with a significant difference, followed by groups 2, 4, and lastly 1 ( P < 0.001 ).
Furthermore, groups 2 and 3 compared to groups 1 and 4 had the least overall dose of analgesics and requested them the latest, with a significant difference ( P < 0.05 ).
Conclusion.
Local anesthesia (1 mL of ketamine plus 2 mL of bupivacaine 0.5% or 1 mL of normal saline plus 2 mL of bupivacaine 0.5%) combined with spinal anesthesia reduces postoperative pain and leads to greater comfort in recovering patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kazemeini, Alireza& Rahimi, Mojgan& Fazeli, Sadegh Mohammad& Mirjafari, Seyedeh Adeleh& Ghaderi, Hamid& Fani, Kamal…[et al.]. 2014. The Effect of Local Injections of Bupivacaine Plus Ketamine, Bupivacaine Alone, and Placebo on Reducing Postoperative Anal Fistula Pain: A Randomized Clinical Trial. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1049583
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kazemeini, Alireza…[et al.]. The Effect of Local Injections of Bupivacaine Plus Ketamine, Bupivacaine Alone, and Placebo on Reducing Postoperative Anal Fistula Pain: A Randomized Clinical Trial. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1049583
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kazemeini, Alireza& Rahimi, Mojgan& Fazeli, Sadegh Mohammad& Mirjafari, Seyedeh Adeleh& Ghaderi, Hamid& Fani, Kamal…[et al.]. The Effect of Local Injections of Bupivacaine Plus Ketamine, Bupivacaine Alone, and Placebo on Reducing Postoperative Anal Fistula Pain: A Randomized Clinical Trial. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1049583
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1049583
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر