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Phytochemical Analysis, Antioxidant, Antistress, and Nootropic Activities of Aqueous and Methanolic Seed Extracts of Ladies Finger (Abelmoschus esculentus L.) in Mice
المؤلفون المشاركون
Doreddula, Sathish Kumar
Bonam, Srinivasa Reddy
Gaddam, Durga Prasad
Desu, Brahma Srinivasa Rao
Ramarao, Nadendla
Pandy, Vijayapandi
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-21
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Abelmoschus esculentus L.
(ladies finger, okra) is a well-known tropical vegetable, widely planted from Africa to Asia and from South Europe to America.
In the present study, we investigated the in vitro antioxidant capacity and in vivo protective effect of the aqueous and methanolic seed extracts of Abelmoschus esculentus against scopolamine-induced cognitive impairment using passive avoidance task and acute restraining stress-induced behavioural and biochemical changes using elevated plus maze (EPM) and forced swimming test (FST) in mice.
Our results demonstrated that the pretreatment of mice with aqueous and methanolic seed extracts of Abelmoschus esculentus (200 mg/kg, p.o.) for seven days significantly (P< 0.01) attenuated scopolamine-induced cognitive impairment in the passive avoidance test.
In addition, these extracts significantly reduced the blood glucose, corticosterone, cholesterol, and triglyceride levels elevated by acute restraint stress and also significantly increased the time spent in open arm in EPM and decreased the immobility time in FST.
It has also been revealed that these extracts showed a significant antioxidant activity and no signs of toxicity or death up to a dose of 2000 mg/kg, p.o.
These results suggest that the seed extracts of Abelmoschus esculentus L.
possess antioxidant, antistress, and nootropic activities which promisingly support the medicinal values of ladies finger as a vegetable.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Doreddula, Sathish Kumar& Bonam, Srinivasa Reddy& Gaddam, Durga Prasad& Desu, Brahma Srinivasa Rao& Ramarao, Nadendla& Pandy, Vijayapandi. 2014. Phytochemical Analysis, Antioxidant, Antistress, and Nootropic Activities of Aqueous and Methanolic Seed Extracts of Ladies Finger (Abelmoschus esculentus L.) in Mice. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1049947
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Doreddula, Sathish Kumar…[et al.]. Phytochemical Analysis, Antioxidant, Antistress, and Nootropic Activities of Aqueous and Methanolic Seed Extracts of Ladies Finger (Abelmoschus esculentus L.) in Mice. The Scientific World Journal No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-1049947
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Doreddula, Sathish Kumar& Bonam, Srinivasa Reddy& Gaddam, Durga Prasad& Desu, Brahma Srinivasa Rao& Ramarao, Nadendla& Pandy, Vijayapandi. Phytochemical Analysis, Antioxidant, Antistress, and Nootropic Activities of Aqueous and Methanolic Seed Extracts of Ladies Finger (Abelmoschus esculentus L.) in Mice. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1049947
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1049947
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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