Clinical and Renal Biopsy Findings Predicting Outcome in Renal Thrombotic Microangiopathy: A Large Cohort Study from a Single Institute in China
المؤلفون المشاركون
Zhao, Ming-hui
Song, Di
Yu, Feng
YU, Xiao-Juan
Wang, Su-Xia
Song, Yan
Liu, Gang
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-11
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Objective.
The current study aimed to investigate the spectrum of etiologies and associated disorders of renal biopsy-proven thrombotic microangiopathy (TMA) patients.
Methods.
The clinical, laboratory, and renal histopathological data of patients with renal TMA from 2000 to 2012 in our institute were collected and reviewed.
Results.
One hundred and nine TMA patients were enrolled in this study.
The mean age was 34.0 ± 11.1 years.
Seventy patients (64.2%) were male and thirty-nine patients (35.8%) were female.
There were eight patients (7.3%) with hemolytic uremic syndrome (HUS).
Sixty-one patients (56.0%) were secondary to malignant hypertension.
Fourteen patients (12.8%) were pregnancy-associated TMA.
Other associated disorders included 17 patients with connective tissue disorders, 2 patients with hematopoietic stem cell transplantation, 4 patients with Castleman’s disease, 1 patient with cryoglobulinemia, and 2 patients with glomerulopathy.
During followup, 8 patients died due to severe infection, 17 patients had doubling of serum creatinine, and 44 had end-stage renal disease.
In multivariate analysis, male, elevated serum creatinine, and decreased hemoglobin were independently associated with poor renal outcomes.
Conclusions.
Renal TMA changes consisted of different disorders with various etiologies.
aHUS, pregnancy-associated TMA, and malignant hypertension accounted for the majority of patients in our cohort.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
YU, Xiao-Juan& Yu, Feng& Song, Di& Wang, Su-Xia& Song, Yan& Liu, Gang…[et al.]. 2014. Clinical and Renal Biopsy Findings Predicting Outcome in Renal Thrombotic Microangiopathy: A Large Cohort Study from a Single Institute in China. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1050586
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
YU, Xiao-Juan…[et al.]. Clinical and Renal Biopsy Findings Predicting Outcome in Renal Thrombotic Microangiopathy: A Large Cohort Study from a Single Institute in China. The Scientific World Journal No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1050586
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
YU, Xiao-Juan& Yu, Feng& Song, Di& Wang, Su-Xia& Song, Yan& Liu, Gang…[et al.]. Clinical and Renal Biopsy Findings Predicting Outcome in Renal Thrombotic Microangiopathy: A Large Cohort Study from a Single Institute in China. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1050586
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1050586
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر