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Diversity and Antimicrobial Activities of Actinobacteria Isolated from Tropical Mangrove Sediments in Malaysia
المؤلفون المشاركون
Lee, Learn-Han
Zainal, Nurullhudda
Azman, Adzzie-Shazleen
Eng, Shu-Kee
Goh, Bey-Hing
Yin, Wai-Fong
Ab Mutalib, Nurul-Syakima
Chan, Kok-Gan
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-05
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
The aim of this study was to isolate and identify Actinobacteria from Malaysia mangrove forest and screen them for production of antimicrobial secondary metabolites.
Eighty-seven isolates were isolated from soil samples collected at 4 different sites.
This is the first report to describe the isolation of Streptomyces, Mycobacterium, Leifsonia, Microbacterium, Sinomonas, Nocardia, Terrabacter, Streptacidiphilus, Micromonospora, Gordonia, and Nocardioides from mangrove in east coast of Malaysia.
Of 87 isolates, at least 5 isolates are considered as putative novel taxa.
Nine Streptomyces sp.
isolates were producing potent antimicrobial secondary metabolites, indicating that Streptomyces isolates are providing high quality metabolites for drug discovery purposes.
The discovery of a novel species, Streptomyces pluripotens sp.
nov.
MUSC 135T that produced potent secondary metabolites inhibiting the growth of MRSA, had provided promising metabolites for drug discovery research.
The biosynthetic potential of 87 isolates was investigated by the detection of polyketide synthetase (PKS) and nonribosomal polyketide synthetase (NRPS) genes, the hallmarks of secondary metabolites production.
Results showed that many isolates were positive for PKS-I (19.5%), PKS-II (42.5%), and NRPS (5.7%) genes, indicating that mangrove Actinobacteria have significant biosynthetic potential.
Our results highlighted that mangrove environment represented a rich reservoir for isolation of Actinobacteria, which are potential sources for discovery of antimicrobial secondary metabolites.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lee, Learn-Han& Zainal, Nurullhudda& Azman, Adzzie-Shazleen& Eng, Shu-Kee& Goh, Bey-Hing& Yin, Wai-Fong…[et al.]. 2014. Diversity and Antimicrobial Activities of Actinobacteria Isolated from Tropical Mangrove Sediments in Malaysia. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1050664
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lee, Learn-Han…[et al.]. Diversity and Antimicrobial Activities of Actinobacteria Isolated from Tropical Mangrove Sediments in Malaysia. The Scientific World Journal No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-1050664
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lee, Learn-Han& Zainal, Nurullhudda& Azman, Adzzie-Shazleen& Eng, Shu-Kee& Goh, Bey-Hing& Yin, Wai-Fong…[et al.]. Diversity and Antimicrobial Activities of Actinobacteria Isolated from Tropical Mangrove Sediments in Malaysia. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-1050664
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1050664
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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