An In Vitro Synergistic Interaction of Combinations of Thymus glabrescens Essential Oil and Its Main Constituents with Chloramphenicol
المؤلفون المشاركون
Ilić, Budimir S.
Kocić, Branislava D.
Ćirić, Vojislav M.
Cvetković, Olga G.
Miladinović, Dragoljub L.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-28
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
The chemical composition and antibacterial activity of Thymus glabrescens Willd.
(Lamiaceae) essential oil were examined, as well as the association between it and chloramphenicol.
The antibacterial activities of geraniol and thymol, the main constituents of T.
glabrescens oil, individually and in combination with chloramphenicol, were also determined.
The interactions of the essential oil, geraniol, and thymol with chloramphenicol toward five selected strains were evaluated using the microdilution checkerboard assay in combination with chemometric methods.
Oxygenated monoterpenes were the most abundant compound class in the oil, with geraniol (22.33%) as the major compound.
The essential oil exhibited in vitro antibacterial activity against all tested bacterial strains, but the activities were lower than those of the standard antibiotic and thymol.
A combination of T.
glabrescens oil and chloramphenicol produced a strong synergistic interaction (FIC indices in the range 0.21–0.87) and a substantial reduction of the MIC value of chloramphenicol, thus minimizing its adverse side effects.
The combinations geraniol-chloramphenicol and thymol-chloramphenicol produced synergistic interaction to a greater extent, compared with essential oil-chloramphenicol association, which may indicate that the activity of the thyme oil could be attributed to the presence of significant concentrations of geraniol and thymol.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ilić, Budimir S.& Kocić, Branislava D.& Ćirić, Vojislav M.& Cvetković, Olga G.& Miladinović, Dragoljub L.. 2014. An In Vitro Synergistic Interaction of Combinations of Thymus glabrescens Essential Oil and Its Main Constituents with Chloramphenicol. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1051221
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ilić, Budimir S.…[et al.]. An In Vitro Synergistic Interaction of Combinations of Thymus glabrescens Essential Oil and Its Main Constituents with Chloramphenicol. The Scientific World Journal No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1051221
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ilić, Budimir S.& Kocić, Branislava D.& Ćirić, Vojislav M.& Cvetković, Olga G.& Miladinović, Dragoljub L.. An In Vitro Synergistic Interaction of Combinations of Thymus glabrescens Essential Oil and Its Main Constituents with Chloramphenicol. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1051221
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1051221
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر