The Role of 18F-FDG-PET and PETCT in Patients with Colorectal Liver Metastases Undergoing Selective Internal Radiation Therapy with Yttrium-90: A First Evidence-Based Review

الملخص EN

Purpose.

To provide a first evidence-based review of the literature on the role of fluorine-18-fluorodeoxyglucose positron emission tomography and positron emissiontomography/computed tomography (FDG-PET and PET/CT) in patients with colorectal liver metastases (CRLM) undergoing selective internal radiation therapy (SIRT) with yttrium-90 (90Y) microspheres.

Methods.

A comprehensive computer literature search was conducted to find relevant published articles on whole-body FDG-PET or PET/CT in patients with CRLM undergoing SIRT.

Results.

We identified 19 studies including 833 patients with CRLM undergoing SIRT.

The role of FDG-PET or PET/CT was analysed in treatment planning, treatment response evaluation, and as prognostic tool.

Conclusion.

FDG-PET and PET/CT provide additional information in treatment evaluation of CRLM patients treated with SIRT and may have a role in treatment planning and patient selection.

FDG-PET/CT is emerging as good prognostic tool in these patients.