Preoperative Butyrylcholinesterase Level as an Independent Predictor of Overall Survival in Clear Cell Renal Cell Carcinoma Patients Treated with Nephrectomy
المؤلفون المشاركون
Ohyama, Chikara
Mikami, Jotaro
Iwamura, Hiromichi
Fujita, Naoki
Sato, Tendo
Kojima, Yuta
Fukushi, Ken
Yamamoto, Hayato
Hashimoto, Yasuhiro
Kitayama, Masato
Hirota, Kazuyoshi
Imai, Atsushi
Koie, Takuya
Hatakeyama, Shingo
Yoneyama, Takahiro
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-04
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
The prognostic factors for the overall survival (OS) of clear cell renal cell carcinoma (ccRCC) patients treated with nephrectomy are not well defined.
In the present study, we investigated the prognostic significance of preoperative butyrylcholinesterase (BChE) levels in 400 ccRCC patients undergoing radical or partial nephrectomy from 1992 to 2013 at our institution.
Univariate and multivariate analyses were performed to determine the clinical factors associated with OS.
Among the enrolled patients, 302 were diagnosed with organ-confined disease only (T1-2N0M0), 16 with lymph node metastases, and 56 with distant metastases.
The median preoperative BChE level was 250 U/L (normal range, 168–470 U/L), and median follow-up period was 36 months.
The 3-year OS rate in patients with preoperative BChE levels of ≥100 U/L was significantly higher than in those with levels of <100 U/L (89.3% versus 77.7%, P = 0.004 ).
On univariate analysis, performance status; anemia; hypoalbuminemia; preoperative levels of BChE, corrected calcium, and C-reactive protein; and distant metastasis status were significantly associated with OS.
Multivariate analysis revealed that preoperative BChE levels and distant metastasis status were significantly associated with OS.
Our findings suggest a possible role of preoperative BChE levels as an independent predictor of OS after nephrectomy in ccRCC patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sato, Tendo& Kojima, Yuta& Fukushi, Ken& Yamamoto, Hayato& Imai, Atsushi& Hatakeyama, Shingo…[et al.]. 2014. Preoperative Butyrylcholinesterase Level as an Independent Predictor of Overall Survival in Clear Cell Renal Cell Carcinoma Patients Treated with Nephrectomy. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1051711
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sato, Tendo…[et al.]. Preoperative Butyrylcholinesterase Level as an Independent Predictor of Overall Survival in Clear Cell Renal Cell Carcinoma Patients Treated with Nephrectomy. The Scientific World Journal No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1051711
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sato, Tendo& Kojima, Yuta& Fukushi, Ken& Yamamoto, Hayato& Imai, Atsushi& Hatakeyama, Shingo…[et al.]. Preoperative Butyrylcholinesterase Level as an Independent Predictor of Overall Survival in Clear Cell Renal Cell Carcinoma Patients Treated with Nephrectomy. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1051711
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1051711
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر