Initial In Vivo Evaluation of a Novel Left Ventricular Assist Device
المؤلفون المشاركون
Wu, Guanghui
Lin, Changyan
Li, Haiyang
Hou, Xiaotong
Chen, Chen
Liu, Xiujian
Xu, Chuangye
Wang, Jing
Yang, Peng
Qu, Wenbo
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-11
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The aim of the study was to use the ovine model to evaluate the hemocompatibility and end-organ effects of a newly developed magnetic suspension centrifugal left ventricular assist device (LVAD) by CH Biomedical Inc., Jiangsu, China.
The LVADs were implanted in 6 healthy sheep, where inflow was inserted into the left ventricular apex and outflow was anastomosed to the descending aorta.
All sheep received anticoagulation and antiaggregation therapy during the study.
Hematologic and biochemical tests were performed to evaluate anemia, hepatorenal function, and the extent of hemolysis.
The experiments lasted for up to 30 days on the beating hearts.
All sheep were humanely killed at the termination of the experiments, and the end-organs were examined macroscopically and histopathologically.
Autopsy was performed in all animals and there was no thrombus formation observed inside the pump.
The pump’s inflow and outflow conduits were also free of thrombus.
Hematologic and biochemical test results were within normal limits during the study period.
Postmortem examination of the explanted organs revealed no evidence of ischemia or infarction.
Based on the in vivo study, this LVAD is suitable for implantation and can provide efficient support with good biocompatibility.
The encouraging results in this study suggest that it is feasible to evaluate the device’s long-term durability and stability.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Guanghui& Lin, Changyan& Li, Haiyang& Hou, Xiaotong& Chen, Chen& Liu, Xiujian…[et al.]. 2015. Initial In Vivo Evaluation of a Novel Left Ventricular Assist Device. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054368
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Guanghui…[et al.]. Initial In Vivo Evaluation of a Novel Left Ventricular Assist Device. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1054368
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Guanghui& Lin, Changyan& Li, Haiyang& Hou, Xiaotong& Chen, Chen& Liu, Xiujian…[et al.]. Initial In Vivo Evaluation of a Novel Left Ventricular Assist Device. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054368
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1054368
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر