Effect of Dietary Lead on Intestinal Nutrient Transporters mRNA Expression in Broiler Chickens
المؤلفون المشاركون
Faseleh Jahromi, Mohammad
Soleimani Farjam, Abdoreza
Ebrahimi, Roohollah
Idrus, Zulkifli
Liang, Juan Boo
Shokryazdan, Parisa
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-28
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Lead- (Pb-) induced oxidative stress is known to suppress growth performance and feed efficiency in broiler chickens.
In an attempt to describe the specific underlying mechanisms of such phenomenon we carried out the current study.
Ninety-six one-day-old broiler chicks were randomly assigned to 2 dietary treatment groups of 6 pen replicates, namely, (i) basal diet containing no lead supplement (control) and (ii) basal diet containing 200 mg lead acetate/kg of diet.
Following 3 weeks of experimental period, jejunum samples were collected to examine the changes in gene expression of several nutrient transporters, antioxidant enzymes, and heat shock protein 70 (Hsp70) using quantitative real-time PCR.
The results showed that addition of lead significantly decreased feed intake, body weight gain, and feed efficiency.
Moreover, with the exception of GLUT5, the expression of all sugar, peptide, and amino acid transporters was significantly downregulated in the birds under Pb induced oxidative stress.
Exposure to Pb also upregulated the antioxidant enzymes gene expression together with the downregulation of glutathione S-transferase and Hsp70.
In conclusion, it appears that Pb-induced oxidative stress adversely suppresses feed efficiency and growth performance in chicken and the possible underlying mechanism for such phenomenon is downregulation of major nutrient transporter genes in small intestine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ebrahimi, Roohollah& Faseleh Jahromi, Mohammad& Liang, Juan Boo& Soleimani Farjam, Abdoreza& Shokryazdan, Parisa& Idrus, Zulkifli. 2015. Effect of Dietary Lead on Intestinal Nutrient Transporters mRNA Expression in Broiler Chickens. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1054375
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ebrahimi, Roohollah…[et al.]. Effect of Dietary Lead on Intestinal Nutrient Transporters mRNA Expression in Broiler Chickens. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1054375
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ebrahimi, Roohollah& Faseleh Jahromi, Mohammad& Liang, Juan Boo& Soleimani Farjam, Abdoreza& Shokryazdan, Parisa& Idrus, Zulkifli. Effect of Dietary Lead on Intestinal Nutrient Transporters mRNA Expression in Broiler Chickens. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1054375
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1054375
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر