The Expression and Distributions of ANP32A in the Developing Brain
المؤلفون المشاركون
Li, Jin-Feng
Zhang, Da-Jin
Liu, Xin-Shan
Wang, Shan-Shan
Liu, Xinshan
Wang, Fuyu
Ma, Xiaodong
Cui, Chunping
Shi, Chenghe
Wang, Yunliang
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-19
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A (ANP32A), has multiple functions involved in neuritogenesis, transcriptional regulation, and apoptosis.
However, whether ANP32A has an effect on the mammalian developing brain is still in question.
In this study, it was shown that brain was the organ that expressed the most abundant ANP32A by human multiple tissue expression (MTE) array.
The distribution of ANP32A in the different adult brain areas was diverse dramatically, with high expression in cerebellum, temporal lobe, and cerebral cortex and with low expression in pons, medulla oblongata, and spinal cord.
The expression of ANP32A was higher in the adult brain than in the fetal brain of not only humans but also mice in a time-dependent manner.
ANP32A signals were dispersed accordantly in embryonic mouse brain.
However, ANP32A was abundant in the granular layer of the cerebellum and the cerebral cortex when the mice were growing up, as well as in the Purkinje cells of the cerebellum.
The variation of expression levels and distribution of ANP32A in the developing brain would imply that ANP32A may play an important role in mammalian brain development, especially in the differentiation and function of neurons in the cerebellum and the cerebral cortex.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Shan-Shan& Wang, Yunliang& Liu, Xin-Shan& Liu, Xinshan& Wang, Fuyu& Ma, Xiaodong…[et al.]. 2015. The Expression and Distributions of ANP32A in the Developing Brain. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1054632
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Shan-Shan…[et al.]. The Expression and Distributions of ANP32A in the Developing Brain. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1054632
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Shan-Shan& Wang, Yunliang& Liu, Xin-Shan& Liu, Xinshan& Wang, Fuyu& Ma, Xiaodong…[et al.]. The Expression and Distributions of ANP32A in the Developing Brain. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1054632
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1054632
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر