![](/images/graphics-bg.png)
Phenotypic Characteristics Associated with Virulence of Clinical Isolates from the Sporothrix Complex
المؤلفون المشاركون
Nosanchuk, Joshua Daniel
Almeida-Paes, Rodrigo
de Oliveira, Luã Cardoso
Oliveira, Manoel Marques Evangelista
Gutierrez-Galhardo, Maria Clara
Zancopé-Oliveira, Rosely Maria
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-04-19
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The Sporothrix complex members cause sporotrichosis, a subcutaneous mycosis with a wide spectrum of clinical manifestations.
Several specific phenotypic characteristics are associated with virulence in many fungi, but studies in this field involving the Sporothrix complex species are scarce.
Melanization, thermotolerance, and production of proteases, catalase, and urease were investigated in 61 S.
brasiliensis, one S.
globosa, and 10 S.
schenckii strains.
The S.
brasiliensis strains showed a higher expression of melanin and urease compared with S.
schenckii.
These two species, however, presented similar thermotolerances.
Our S.
globosa strain had low expression of all studied virulence factors.
The relationship between these phenotypes and clinical aspects of sporotrichosis was also evaluated.
Strains isolated from patients with spontaneous regression of infection were heavily melanized and produced high urease levels.
Melanin was also related to dissemination of internal organs and protease production was associated with HIV-coinfection.
A murine sporotrichosis model showed that a S.
brasiliensis strain with high expression of virulence factors was able to disseminate and yield a high fungal burden in comparison with a control S.
schenckii strain.
Our results show that virulence-related phenotypes are variably expressed within the Sporothrix complex species and might be involved in clinical aspects of sporotrichosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Almeida-Paes, Rodrigo& de Oliveira, Luã Cardoso& Oliveira, Manoel Marques Evangelista& Gutierrez-Galhardo, Maria Clara& Nosanchuk, Joshua Daniel& Zancopé-Oliveira, Rosely Maria. 2015. Phenotypic Characteristics Associated with Virulence of Clinical Isolates from the Sporothrix Complex. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1054646
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Almeida-Paes, Rodrigo…[et al.]. Phenotypic Characteristics Associated with Virulence of Clinical Isolates from the Sporothrix Complex. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1054646
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Almeida-Paes, Rodrigo& de Oliveira, Luã Cardoso& Oliveira, Manoel Marques Evangelista& Gutierrez-Galhardo, Maria Clara& Nosanchuk, Joshua Daniel& Zancopé-Oliveira, Rosely Maria. Phenotypic Characteristics Associated with Virulence of Clinical Isolates from the Sporothrix Complex. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1054646
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1054646
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)