Prevention of Polyglycolic Acid-Induced Peritoneal Adhesions Using Alginate in a Rat Model
المؤلفون المشاركون
Matoba, Mari
Hashimoto, Ayumi
Tanzawa, Ayumi
Orikasa, Taichi
Ikeda, Junki
Iwame, Yoshizumi
Ozamoto, Yuki
Abe, Rie
Miyamoto, Hiroe
Yoshida, Chiko
Hashimoto, Toru
Torii, Hiroko
Takamori, Hideki
Morita, Shinichiro
Tsujimoto, Hiroyuki
Hagiwara, Akeo
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-21
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Postoperative intra-abdominal or intrathoracic adhesions sometimes cause significant morbidity.
We have designed three types of alginate-based treatments using strongly cross-linked (SL), weakly cross-linked (WL), and non-cross-linked (NL) alginate with calcium gluconate.
In rat experiments, we compared the antiadhesive effects of the three types of alginate-based treatments, fibrin glue treatment (a standard treatment), and no treatment against adhesions caused by polyglycolic acid (PGA) mesh (PGA-induced adhesions).
The antiadhesive materials were set on the PGA sheet fixed on the parietal peritoneum of the abdomen.
Fifty-six days later, the adhesions were evaluated macroscopically by the adhesion scores and microscopically by hematoxylin-eosin staining and immunostaining.
We also tested the fibroblast growth on the surface of the antiadhesive materials in vitro.
The antiadhesive effects of WL and NL were superior to the no treatment and fibrin glue treatment.
A microscopic evaluation confirmed that the PGA sheet was covered by a peritoneal layer constructed of well-differentiated mesothelial cells, and the inflammation was most improved in the NL and WL.
The fibroblast growth was inhibited most on the surfaces of the NL and WL.
These results suggest that either the WL or NL treatments are suitable for preventing PGA-induced adhesions compared to SL or the conventional treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Matoba, Mari& Hashimoto, Ayumi& Tanzawa, Ayumi& Orikasa, Taichi& Ikeda, Junki& Iwame, Yoshizumi…[et al.]. 2015. Prevention of Polyglycolic Acid-Induced Peritoneal Adhesions Using Alginate in a Rat Model. BioMed Research International،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1055348
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Matoba, Mari…[et al.]. Prevention of Polyglycolic Acid-Induced Peritoneal Adhesions Using Alginate in a Rat Model. BioMed Research International No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1055348
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Matoba, Mari& Hashimoto, Ayumi& Tanzawa, Ayumi& Orikasa, Taichi& Ikeda, Junki& Iwame, Yoshizumi…[et al.]. Prevention of Polyglycolic Acid-Induced Peritoneal Adhesions Using Alginate in a Rat Model. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1055348
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055348
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر