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Analgesic Effects of Intra-Articular BupivacaineIntravenous Parecoxib Combination Therapy versus Intravenous Parecoxib Monotherapy in Patients Receiving Total Knee Arthroplasty: A Randomized, Double-Blind Trial
المؤلفون المشاركون
Yu, Huang-Ping
Shen, Shih-Jyun
Peng, Pei-Yu
Chen, Hsiu-Pin
Lin, Jr-Rung
Lee, Mel S.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-11
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objectives.
The purpose of this double-blind, randomized study was to investigate whether the addition of intra-articular bupivacaine to intravenous parecoxib could improve pain relief in patients undergoing total knee arthroplasty.
Methods.
A total of 36 patients undergoing total knee arthroplasty were enrolled into our study.
These patients were randomly allocated either to a placebo-controlled group or study group.
Postoperative pain scores and analgesic consumption were evaluated.
Results.
Numeric rating scale (NRS) data of bupivacaine group in postoperative room were significantly lower than that of control group (control group versus bupivacaine group, 7.9 (6.7–9.1) (mean and 95% confidence interval) versus 4.5 (3.2–5.8) (mean and 95% confidence interval), p=0.001).
NRS data of bupivacaine group in ward were also significantly lower than that of control group.
A significantly lower dose of meperidine was used in the study group postoperatively during the first 24 hours (control group versus bupivacaine group, 3.08 ± 0.80 mg/Kg versus 2.34 ± 0.42 mg/Kg, p=0.001).
Conclusion.
Intra-articular bupivacaine in combination with intravenous parecoxib may improve pain relief and reduce the demand for rescue analgesics in patients undergoing total knee arthroplasty.
The trial is registered with Australian New Zealand Clinical Trials Registry (ACTRN12615000463572).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shen, Shih-Jyun& Peng, Pei-Yu& Chen, Hsiu-Pin& Lin, Jr-Rung& Lee, Mel S.& Yu, Huang-Ping. 2015. Analgesic Effects of Intra-Articular BupivacaineIntravenous Parecoxib Combination Therapy versus Intravenous Parecoxib Monotherapy in Patients Receiving Total Knee Arthroplasty: A Randomized, Double-Blind Trial. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1055508
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shen, Shih-Jyun…[et al.]. Analgesic Effects of Intra-Articular BupivacaineIntravenous Parecoxib Combination Therapy versus Intravenous Parecoxib Monotherapy in Patients Receiving Total Knee Arthroplasty: A Randomized, Double-Blind Trial. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1055508
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shen, Shih-Jyun& Peng, Pei-Yu& Chen, Hsiu-Pin& Lin, Jr-Rung& Lee, Mel S.& Yu, Huang-Ping. Analgesic Effects of Intra-Articular BupivacaineIntravenous Parecoxib Combination Therapy versus Intravenous Parecoxib Monotherapy in Patients Receiving Total Knee Arthroplasty: A Randomized, Double-Blind Trial. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1055508
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055508
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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