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Iron Deposition Is Positively Related to Cognitive Impairment in Patients with Chronic Mild Traumatic Brain Injury: Assessment with Susceptibility Weighted Imaging
المؤلفون المشاركون
Lu, Liyan
Cao, Heli
Wei, Xiaoer
Li, Yuehua
Li, Wenbin
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-20
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
This study aimed to evaluate the usability of SWI in assessment of brain iron to detect cognitive dysfunction in patients with chronic mild traumatic brain injury (mTBI).
Methods.
39 patients with mTBI and 37 normal controls were given the Mini-Mental State Examination (MMSE) and underwent SWI scanning at least 6 months after injury.
Angle radian values were calculated with phase images.
The angle radian values were compared between groups using analysis of covariance, and their association with MMSE scores was analyzed using Spearman correlations.
Results.
Significantly higher angle radian values ( p < 0.05 ) were found in the head of the caudate nucleus, the lenticular nucleus, the hippocampus, the thalamus, the right substantia nigra, the red nucleus, and the splenium of the corpus callosum (SCC) in the mTBI group, compared to the control group.
MMSE scores were negatively correlated with angle radian values in the right substantia nigra ( r = - 0.685 , p < 0.001 ).
Conclusions.
Patients with chronic mTBI might have abnormally high accumulations of iron, and their MMSE scores are negatively associated with angle radian values in the right substantia nigra, suggesting a role of SWI in the assessment of cognitive impairments of these patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lu, Liyan& Cao, Heli& Wei, Xiaoer& Li, Yuehua& Li, Wenbin. 2015. Iron Deposition Is Positively Related to Cognitive Impairment in Patients with Chronic Mild Traumatic Brain Injury: Assessment with Susceptibility Weighted Imaging. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055601
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lu, Liyan…[et al.]. Iron Deposition Is Positively Related to Cognitive Impairment in Patients with Chronic Mild Traumatic Brain Injury: Assessment with Susceptibility Weighted Imaging. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1055601
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lu, Liyan& Cao, Heli& Wei, Xiaoer& Li, Yuehua& Li, Wenbin. Iron Deposition Is Positively Related to Cognitive Impairment in Patients with Chronic Mild Traumatic Brain Injury: Assessment with Susceptibility Weighted Imaging. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055601
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055601
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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