Multiwall Carbon Nanotube-Induced Apoptosis and Antioxidant Gene Expression in the Gills, Liver, and Intestine of Oryzias latipes
المؤلفون المشاركون
Choi, Young Chul
Lee, Jin Wuk
Kim, Rosa
Lee, Sung Kyu
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-03
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Multiwall carbon nanotubes (MWCNTs) have many attractive properties with potential applications in various fields.
Despite their usefulness, however, the associated waste can be hazardous to the environment.
To examine adverse effects in aquatic environments, Oryzias latipes were exposed to MWCNTs dispersed in water for 14 days and apoptosis and antioxidant gene expression were observed.
This work showed that in gills exposed to 100 mg/L MWCNTs for 4 days, there was significant p53, caspase-3 (Cas3), caspase-8 (Cas8), and caspase-9 (Cas9) gene expression relative to the controls, while catalase (CAT) and glutathione-S-transferase (GST) expression were reduced.
At 14 days, CAT, GST, and metallothionein (MT) were induced significantly in the gills and Cas3, Cas8, and Cas9 were induced in the liver.
No significant gene induction was seen in intestine.
Intracellular reactive oxygen species (ROS) were increased significantly only at 14 days.
Histologically, no apoptosis was observed with exposure to 100 mg/L MWCNTs for 21 days.
The gills were more sensitive to MWCNT toxicity than the other organs.
Males had higher apoptosis gene induction than females.
These results demonstrated that MWCNTs could cause apoptosis in a manner influenced by tissue and gender in aqueous environments.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lee, Jin Wuk& Choi, Young Chul& Kim, Rosa& Lee, Sung Kyu. 2015. Multiwall Carbon Nanotube-Induced Apoptosis and Antioxidant Gene Expression in the Gills, Liver, and Intestine of Oryzias latipes. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055657
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lee, Jin Wuk…[et al.]. Multiwall Carbon Nanotube-Induced Apoptosis and Antioxidant Gene Expression in the Gills, Liver, and Intestine of Oryzias latipes. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1055657
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lee, Jin Wuk& Choi, Young Chul& Kim, Rosa& Lee, Sung Kyu. Multiwall Carbon Nanotube-Induced Apoptosis and Antioxidant Gene Expression in the Gills, Liver, and Intestine of Oryzias latipes. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055657
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055657
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر