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Prevalence, Risk Factors, and Genetic Traits in Metabolically Healthy and Unhealthy Obese Individuals
المؤلفون المشاركون
Berezina, A.
Belyaeva, O.
Berkovich, O.
Baranova, E.
Karonova, T.
Bazhenova, E.
Brovin, D.
Shlyakhto, E.
Elena, Grineva
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-04
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To assess prevalence of metabolically healthy individuals among patients with abdominal obesity (AO) and to determine phenotype and potential genetic traits associated with a benign metabolic status.
Methods.
503 AO patients without cardiovascular diseases were examined.
Waist circumference (WC), BMI, blood pressure, plasma glucose and serum insulin levels, HOMA-IR, lipid profile, and adiponectin (AN) and leptin (LEP) concentrations in serum were measured.
Polymorphisms A19G and Q223R of the LEP and LEP receptor gene, and G276T and T45G of the AN gene were investigated.
Results.
91.3% of patients were metabolically unhealthy obese (MUO), and 8.7% metabolically healthy obese (MHO).
MHO patients were younger, and had lesser BMI and WC, while duration of obesity, frequency, and duration of physical training were greater than MUO patients p<0.05.
In MHO and MUO patients distribution of the G19G, G19A, and A19A genotypes of the LEP gene and G276G, G276T, and T276T genotypes of AN gene did not differ.
The Т45Т genotype was associated with increase of metabolic disorders’ risk for patients with АО (OR = 2.331; 95% CI=1.121÷5.132).
Conclusions.
Prevalence of MHO individuals among patients with AO is low.
Benign metabolic status was associated with younger age, lower waist circumference, and higher physical activity, shorter duration of obesity, and G45G adiponectin genotype carriage.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Berezina, A.& Belyaeva, O.& Berkovich, O.& Baranova, E.& Karonova, T.& Bazhenova, E.…[et al.]. 2015. Prevalence, Risk Factors, and Genetic Traits in Metabolically Healthy and Unhealthy Obese Individuals. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055906
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Berezina, A.…[et al.]. Prevalence, Risk Factors, and Genetic Traits in Metabolically Healthy and Unhealthy Obese Individuals. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1055906
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Berezina, A.& Belyaeva, O.& Berkovich, O.& Baranova, E.& Karonova, T.& Bazhenova, E.…[et al.]. Prevalence, Risk Factors, and Genetic Traits in Metabolically Healthy and Unhealthy Obese Individuals. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055906
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055906
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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