Receptor Binding Domain Based HIV Vaccines

الملخص EN

This paper analyzes the main trend of the development of acquired immunodeficiency syndrome (AIDS) vaccines in recent years.

Designing an HIV-1 vaccine that provides robust protection from HIV-1 infection remains a challenge despite many years of effort.

Therefore, we describe the receptor binding domain of gp120 as a target for developing AIDS vaccines.

And we recommend some measures that could induce efficiently and produce cross-reactive neutralizing antibodies with high binding affinity.

Those measures may offer a new way of the research and development of the potent and broad AIDS vaccines.