![](/images/graphics-bg.png)
Impact of a Complex Food Microbiota on Energy Metabolism in the Model Organism Caenorhabditis elegans
المؤلفون المشاركون
Uccelletti, Daniela
Devirgiliis, Chiara
Perozzi, Giuditta
Laudenzi, Chiara
Schifano, Emily
Palleschi, Claudio
Zanni, Elena
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-04-19
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
The nematode Caenorhabditis elegans is widely used as a model system for research on aging, development, and host-pathogen interactions.
Little is currently known about the mechanisms underlying the effects exerted by foodborne microbes.
We took advantage of C.
elegans to evaluate the impact of foodborne microbiota on well characterized physiological features of the worms.
Foodborne lactic acid bacteria (LAB) consortium was used to feed nematodes and its composition was evaluated by 16S rDNA analysis and strain typing before and after colonization of the nematode gut.
Lactobacillus delbrueckii, L.
fermentum, and Leuconostoc lactis were identified as the main species and shown to display different worm gut colonization capacities.
LAB supplementation appeared to decrease nematode lifespan compared to the animals fed with the conventional Escherichia coli nutrient source or a probiotic bacterial strain.
Reduced brood size was also observed in microbiota-fed nematodes.
Moreover, massive accumulation of lipid droplets was revealed by BODIPY staining.
Altered expression of nhr-49, pept-1, and tub-1 genes, associated with obesity phenotypes, was demonstrated by RT-qPCR.
Since several pathways are evolutionarily conserved in C.
elegans, our results highlight the nematode as a valuable model system to investigate the effects of a complex microbial consortium on host energy metabolism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zanni, Elena& Laudenzi, Chiara& Schifano, Emily& Palleschi, Claudio& Perozzi, Giuditta& Uccelletti, Daniela…[et al.]. 2015. Impact of a Complex Food Microbiota on Energy Metabolism in the Model Organism Caenorhabditis elegans. BioMed Research International،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1056162
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zanni, Elena…[et al.]. Impact of a Complex Food Microbiota on Energy Metabolism in the Model Organism Caenorhabditis elegans. BioMed Research International No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1056162
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zanni, Elena& Laudenzi, Chiara& Schifano, Emily& Palleschi, Claudio& Perozzi, Giuditta& Uccelletti, Daniela…[et al.]. Impact of a Complex Food Microbiota on Energy Metabolism in the Model Organism Caenorhabditis elegans. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1056162
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056162
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)