Seven-Day Nonbismuth Containing Quadruple Therapy Could Achieve a Grade “A” Success Rate for First-Line Helicobacter pylori Eradication
المؤلفون المشاركون
Chuah, Seng-Kee
Hu, Tsung-Hui
Lee, Chen-Hsiang
Lu, Lung-Sheng
Hu, Ming-Luen
Kuo, Yuan-Hung
Yen, Yi-Hao
Chiu, Chien-Hua
Kuo, Chung-Huang
Chiu, Yi-Chun
Wu, Keng-Liang
Kuo, Chung-Mou
Chiou, Shue-Shian
Liang, Chih-Ming
Tai, Wei-Chen
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
This prospective study was to assess the efficacy of nonbismuth containing quadruple therapy as first-line H.
pylori treatment and to determine the clinical factors influencing patient outcome.
We enrolled 200 H.
pylori-infected naïve patients.
They were prescribed either a 7-day nonbismuth containing quadruple therapy group (EACM, esomeprazole 40 mg twice daily, amoxicillin 1 g twice daily, metronidazole 500 mg twice daily, and clarithromycin 500 mg twice daily) or a 7-day standard triple therapy group (EAC, esomeprazole 40 mg twice daily, amoxicillin 1 g twice daily, and clarithromycin 500 mg twice daily).
Follow-up studies to assess treatment responses were carried out 8 weeks later.
The eradication rates attained by EACM and EAC groups were 95.6% (95% confidence interval [CI] = 89.4%–98.3%) and 79.3% (95% CI = 70%–86.4%) in the per-protocol analysis (P < 0.001) and 88% (95% CI = 80.2%–93.0%) and 73% (95% I = 63.6%–80.3%) in the intention-to-treat analysis (P = 0.007).
Clarithromycin resistance, metronidazole resistance, and dual clarithromycin and metronidazole resistances were the clinical factors influencing H.
pylori eradication in EACM group.
Clarithromycin resistance and dual clarithromycin and metronidazole resistances were the influential factor for EAC treatment.
In conclusion, the results suggest that 7-day nonbismuth containing quadruple therapy could achieve a grade “A” report card for first-line H.
pylori treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tai, Wei-Chen& Liang, Chih-Ming& Lee, Chen-Hsiang& Chiu, Chien-Hua& Hu, Ming-Luen& Lu, Lung-Sheng…[et al.]. 2015. Seven-Day Nonbismuth Containing Quadruple Therapy Could Achieve a Grade “A” Success Rate for First-Line Helicobacter pylori Eradication. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1056169
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tai, Wei-Chen…[et al.]. Seven-Day Nonbismuth Containing Quadruple Therapy Could Achieve a Grade “A” Success Rate for First-Line Helicobacter pylori Eradication. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1056169
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tai, Wei-Chen& Liang, Chih-Ming& Lee, Chen-Hsiang& Chiu, Chien-Hua& Hu, Ming-Luen& Lu, Lung-Sheng…[et al.]. Seven-Day Nonbismuth Containing Quadruple Therapy Could Achieve a Grade “A” Success Rate for First-Line Helicobacter pylori Eradication. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1056169
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056169
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر