Does Moderate Intensity Exercise Attenuate the Postprandial Lipemic and Airway Inflammatory Response to a High-Fat Meal?

الملخص EN

We investigated whether an acute bout of moderate intensity exercise in the postprandial period attenuates the triglyceride and airway inflammatory response to a high-fat meal (HFM) compared to remaining inactive in the postprandial period.

Seventeen (11 M/6 F) physically active (≥150 min/week of moderate-vigorous physical activity (MVPA)) subjects were randomly assigned to an exercise (EX; 60% VO2peak) or sedentary (CON) condition after a HFM (10 kcal/kg, 63% fat).

Blood analytes and airway inflammation via exhaled nitric oxide (eNO) were measured at baseline, and 2 and 4 hours after HFM.

Airway inflammation was assessed with induced sputum and cell differentials at baseline and 4 hours after HFM.

Triglycerides doubled in the postprandial period (~113 ± 18%, P<0.05), but the increase did not differ between EX and CON.

Percentage of neutrophils was increased 4 hours after HFM (~17%), but the increase did not differ between EX and CON.

Exhaled nitric oxide changed nonlinearly from baseline to 2 and 4 hours after HFM (P<0.05, η2=0.36).

Our findings suggest that, in active individuals, an acute bout of moderate intensity exercise does not attenuate the triglyceride or airway inflammatory response to a high-fat meal.