![](/images/graphics-bg.png)
Volumetric MR-Guided High-Intensity Focused Ultrasound with Direct Skin Cooling for the Treatment of Symptomatic Uterine Fibroids: Proof-of-Concept Study
المؤلفون المشاركون
van den Bosch, M. A. A. J.
Ikink, Marlijne E.
van Breugel, Johanna M. M.
Schubert, Gerald
Nijenhuis, Robbert J.
Bartels, Lambertus W.
Moonen, Chrit T. W.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-30
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objective.
To prospectively assess the safety and technical feasibility of volumetric magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) ablation with direct skin cooling (DISC) during treatment of uterine fibroids.
Methods.
In this proof-of-concept study, eight patients were consecutively selected for clinical MR-HIFU ablation of uterine fibroids with the use of an additional DISC device to maintain a constant temperature (T≈20°C) at the interface between the HIFU table top and the skin.
Technical feasibility was verified by successful completion of MR-HIFU ablation.
Contrast-enhanced T1-weighted MRI was used to measure the treatment effect (nonperfused volume (NPV) ratio).
Safety was evaluated by recording of adverse events (AEs) within 30 days’ follow-up.
Results.
All MR-HIFU treatments were successfully completed in an outpatient setting.
The median NPV ratio was 0.56 (IQR [0.27–0.72]).
Immediately after treatment, two patients experienced coldness related discomfort which resolved at the same day.
No serious (device-related) AEs were reported.
Specifically, no skin burns, cold injuries, or subcutaneous edema were observed.
Conclusion.
This study showed that it is safe and technically feasible to complete a volumetric MR-HIFU ablation with DISC.
This technique may reduce the risk of thermal injury to the abdominal wall during MR-HIFU ablation of uterine fibroids.
This trial is registered with NTR4189.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ikink, Marlijne E.& van Breugel, Johanna M. M.& Schubert, Gerald& Nijenhuis, Robbert J.& Bartels, Lambertus W.& Moonen, Chrit T. W.…[et al.]. 2015. Volumetric MR-Guided High-Intensity Focused Ultrasound with Direct Skin Cooling for the Treatment of Symptomatic Uterine Fibroids: Proof-of-Concept Study. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1056377
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ikink, Marlijne E.…[et al.]. Volumetric MR-Guided High-Intensity Focused Ultrasound with Direct Skin Cooling for the Treatment of Symptomatic Uterine Fibroids: Proof-of-Concept Study. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1056377
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ikink, Marlijne E.& van Breugel, Johanna M. M.& Schubert, Gerald& Nijenhuis, Robbert J.& Bartels, Lambertus W.& Moonen, Chrit T. W.…[et al.]. Volumetric MR-Guided High-Intensity Focused Ultrasound with Direct Skin Cooling for the Treatment of Symptomatic Uterine Fibroids: Proof-of-Concept Study. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1056377
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056377
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)