WHO Multidrug Therapy for Leprosy: Epidemiology of Default in Treatment in Agra District, Uttar Pradesh, India
المؤلفون المشاركون
Kumar, Anil
Girdhar, Anita
Chakma, Joy Kumar
Girdhar, Bhuwneswar Kumar
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-01
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim.
To study the magnitude of default, time of default, its causes, and final clinical outcome.
Methods.
Data collected in active surveys in Agra is analyzed.
Patients were given treatment after medical confirmation and were followed up.
The treatment default and other clinical outcomes were recorded.
Results.
Patients who defaulted have comparable demographic characteristics.
However, among defaulters more women (62.7% in PB, 42.6% in MB) were seen than those in treatment completers (PB 52.7% and MB 35.9%).
Nerve involvement was high in treatment completers: 45.7% in PB and 91.3% in MB leprosy.
Overall default rate was lower (14.8%) in ROM than (28.8%) in standard MDT for PB leprosy ( χ 1 2 = 11.6 , P = 0.001 ) and also for MB leprosy: 9.1% in ROM compared to 34.5% in MDT ( χ 1 2 = 6.0 , P = 0.015 ).
Default rate was not different (28.8% versus 34.5%, P > 0.05 ) in both types of leprosy given MDT.
Most patients defaulted at early stage of treatment and mainly due to manageable side effects.
Conclusion.
The default in standard MDT both for PB and MB leprosy was observed to be significantly higher than in ROM treatment.
Most defaults occurred at early stage of treatment and major contribution of default is due to side effects like drowsiness, weakness, vomiting, diarrhea, and so forth, related to poor general health.
Although about half of the defaulters were observed to be cured 2.2% in PB-MDT and 10.9% of MB-MDT developed disability.
This is an issue due to default.
Attempts are needed to increase treatment compliance.
The use of specially designed disease related health education along with easily administered drug regimens may help to reduce default.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kumar, Anil& Girdhar, Anita& Chakma, Joy Kumar& Girdhar, Bhuwneswar Kumar. 2015. WHO Multidrug Therapy for Leprosy: Epidemiology of Default in Treatment in Agra District, Uttar Pradesh, India. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056439
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kumar, Anil…[et al.]. WHO Multidrug Therapy for Leprosy: Epidemiology of Default in Treatment in Agra District, Uttar Pradesh, India. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056439
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kumar, Anil& Girdhar, Anita& Chakma, Joy Kumar& Girdhar, Bhuwneswar Kumar. WHO Multidrug Therapy for Leprosy: Epidemiology of Default in Treatment in Agra District, Uttar Pradesh, India. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056439
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056439
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر