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Normal Hearing Ability but Impaired Auditory Selective Attention Associated with Prediction of Response to Donepezil in Patients with Alzheimer’s Disease
المؤلفون المشاركون
Yamaguchi, Satoshi
Meguro, Kenichi
Ouchi, Yoshitaka
Kato, Yuriko
Akanuma, Kyoko
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-16
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Alzheimer’s disease (AD) patients have a poor response to the voices of caregivers.
After administration of donepezil, caregivers often find that patients respond more frequently, whereas they had previously pretended to be “deaf.” We investigated whether auditory selective attention is associated with response to donepezil.
Methods.
The subjects were40 AD patients, 20 elderly healthy controls (HCs), and 15 young HCs.
Pure tone audiometry was conducted and an original Auditory Selective Attention (ASA) test was performed with a MoCA vigilance test.
Reassessment of the AD group was performed after donepezil treatment for 3 months.
Results.
Hearing level of the AD group was the same as that of the elderly HC group.
However, ASA test scores decreased in the AD group and were correlated with the vigilance test scores.
Donepezil responders (MMSE 3+) also showed improvement on the ASA test.
At baseline, the responders had higher vigilance and lower ASA test scores.
Conclusion.
Contrary to the common view, AD patients had a similar level of hearing ability to healthy elderly.
Auditory attention was impaired in AD patients, which suggests that unnecessary sounds should be avoided in nursing homes.
Auditory selective attention is associated with response to donepezil in AD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ouchi, Yoshitaka& Meguro, Kenichi& Akanuma, Kyoko& Kato, Yuriko& Yamaguchi, Satoshi. 2015. Normal Hearing Ability but Impaired Auditory Selective Attention Associated with Prediction of Response to Donepezil in Patients with Alzheimer’s Disease. Behavioural Neurology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1057552
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ouchi, Yoshitaka…[et al.]. Normal Hearing Ability but Impaired Auditory Selective Attention Associated with Prediction of Response to Donepezil in Patients with Alzheimer’s Disease. Behavioural Neurology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1057552
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ouchi, Yoshitaka& Meguro, Kenichi& Akanuma, Kyoko& Kato, Yuriko& Yamaguchi, Satoshi. Normal Hearing Ability but Impaired Auditory Selective Attention Associated with Prediction of Response to Donepezil in Patients with Alzheimer’s Disease. Behavioural Neurology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1057552
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1057552
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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