Loss in Executive Functioning Best Explains Changes in Pain Responsiveness in Patients with Dementia-Related Cognitive Decline
المؤلفون المشاركون
Lautenbacher, Stefan
Mylius, Veit
Schepelmann, Karsten
Kunz, Miriam
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
There is ample evidence that dementia changes the processing of pain.
However, it is not known whether this change in pain processing is related to the general decline in cognitive functioning or whether it may be related to specific domains of cognitive functioning.
With the present study we tried to answer this question.
We assessed different cognitive domains (orientation, memory, abstract thinking/executive function, aphasia and apraxia, and information processing speed) in 70 older patients with cognitive impairment (mild cognitive impairment up to moderate degrees of dementia).
Pain responsiveness was assessed by measuring the nociceptive flexion reflex (NFR) threshold and facial responses to noxious electrical stimulation.
Using regression analyses, we assessed which domain of cognitive functioning best predicted variance in pain responsiveness.
Variance in pain responsiveness (NFR and facial expressions) was best explained by those items assessing executive functioning even when controlling for overall cognitive performance and memory functioning.
The close association between executive functioning and pain responsiveness suggests that dementia-related neurodegeneration in prefrontal areas might result not only in reduced executive functioning but also in a loss of pain inhibitory potency, rendering the patient more vulnerable to pain.
Our findings also suggest that pain assessment in dementia should be regularly completed by tests of cognitive functions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kunz, Miriam& Mylius, Veit& Schepelmann, Karsten& Lautenbacher, Stefan. 2015. Loss in Executive Functioning Best Explains Changes in Pain Responsiveness in Patients with Dementia-Related Cognitive Decline. Behavioural Neurology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057585
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kunz, Miriam…[et al.]. Loss in Executive Functioning Best Explains Changes in Pain Responsiveness in Patients with Dementia-Related Cognitive Decline. Behavioural Neurology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057585
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kunz, Miriam& Mylius, Veit& Schepelmann, Karsten& Lautenbacher, Stefan. Loss in Executive Functioning Best Explains Changes in Pain Responsiveness in Patients with Dementia-Related Cognitive Decline. Behavioural Neurology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057585
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1057585
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر