Distribution of Phenolic Contents, Antidiabetic Potentials, Antihypertensive Properties, and Antioxidative Effects of Soursop (Annona muricata L.) Fruit Parts In Vitro
المؤلفون المشاركون
Oyeleye, Idowu S.
Adefegha, Stephen A.
Oboh, Ganiyu
المصدر
Biochemistry Research International
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-15
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Soursop fruit has been used in folklore for the management of type-2 diabetes and hypertension with limited information on the scientific backing.
This study investigated the effects of aqueous extracts (1 : 100 w/v) of Soursop fruit part (pericarp, pulp, and seed) on key enzymes linked to type-2 diabetes (α-amylase and α-glucosidase) and hypertension [angiotensin-I converting enzyme (ACE)].
Radicals scavenging and Fe2+ chelation abilities and reducing property as well as phenolic contents of the extracts were also determined.
Our data revealed that the extracts inhibited α-amylase and α-glucosidase and ACE activities dose-dependently.
The effective concentration of the extract causing 50% antioxidant activity (EC50) revealed that pericarp extract had the highest α-amylase (0.46 mg/mL), α-glucosidase (0.37 mg/mL), and ACE (0.03 mg/mL) inhibitory activities while the seed extract had the least [α-amylase (0.76 mg/mL); α-glucosidase (0.73 mg/mL); and ACE (0.20 mg/mL)].
Furthermore, the extracts scavenged radicals, reduced Fe3+ to Fe2+, and chelated Fe2+.
The phenolic contents in the extracts ranged from 85.65 to 560.21 mg/100 g.
The enzymes inhibitory and antioxidants potentials of the extracts could be attributed to their phenolic distributions which could be among the scientific basis for their use in the management of diabetes and hypertension.
However, the pericarp appeared to be most promising.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Adefegha, Stephen A.& Oyeleye, Idowu S.& Oboh, Ganiyu. 2015. Distribution of Phenolic Contents, Antidiabetic Potentials, Antihypertensive Properties, and Antioxidative Effects of Soursop (Annona muricata L.) Fruit Parts In Vitro. Biochemistry Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1057610
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Adefegha, Stephen A.…[et al.]. Distribution of Phenolic Contents, Antidiabetic Potentials, Antihypertensive Properties, and Antioxidative Effects of Soursop (Annona muricata L.) Fruit Parts In Vitro. Biochemistry Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1057610
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Adefegha, Stephen A.& Oyeleye, Idowu S.& Oboh, Ganiyu. Distribution of Phenolic Contents, Antidiabetic Potentials, Antihypertensive Properties, and Antioxidative Effects of Soursop (Annona muricata L.) Fruit Parts In Vitro. Biochemistry Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1057610
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1057610
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر