Towards Automated Three-Dimensional Tracking of Nephrons through Stacked Histological Image Sets
المؤلفون المشاركون
Bhikha, Charita
Andreasen, Arne
Christensen, Erik I.
Letts, Robyn F. R.
Pantanowitz, Adam
Rubin, David M.
Thomsen, Jesper S.
Zhai, Xiao-Yue
المصدر
Computational and Mathematical Methods in Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-15
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
An automated approach for tracking individual nephrons through three-dimensional histological image sets of mouse and rat kidneys is presented.
In a previous study, the available images were tracked manually through the image sets in order to explore renal microarchitecture.
The purpose of the current research is to reduce the time and effort required to manually trace nephrons by creating an automated, intelligent system as a standard tool for such datasets.
The algorithm is robust enough to isolate closely packed nephrons and track their convoluted paths despite a number of nonideal, interfering conditions such as local image distortions, artefacts, and interstitial tissue interference.
The system comprises image preprocessing, feature extraction, and a custom graph-based tracking algorithm, which is validated by a rule base and a machine learning algorithm.
A study of a selection of automatically tracked nephrons, when compared with manual tracking, yields a 95% tracking accuracy for structures in the cortex, while those in the medulla have lower accuracy due to narrower diameter and higher density.
Limited manual intervention is introduced to improve tracking, enabling full nephron paths to be obtained with an average of 17 manual corrections per mouse nephron and 58 manual corrections per rat nephron.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bhikha, Charita& Andreasen, Arne& Christensen, Erik I.& Letts, Robyn F. R.& Pantanowitz, Adam& Rubin, David M.…[et al.]. 2015. Towards Automated Three-Dimensional Tracking of Nephrons through Stacked Histological Image Sets. Computational and Mathematical Methods in Medicine،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1057928
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bhikha, Charita…[et al.]. Towards Automated Three-Dimensional Tracking of Nephrons through Stacked Histological Image Sets. Computational and Mathematical Methods in Medicine No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1057928
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bhikha, Charita& Andreasen, Arne& Christensen, Erik I.& Letts, Robyn F. R.& Pantanowitz, Adam& Rubin, David M.…[et al.]. Towards Automated Three-Dimensional Tracking of Nephrons through Stacked Histological Image Sets. Computational and Mathematical Methods in Medicine. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1057928
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1057928
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر