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Myasthenic Crisis in an Elderly Patient with Positive Antibodies against Acetylcholine and Anti-MuSK, Successfully Treated with Noninvasive Mechanical Ventilation
المؤلفون المشاركون
Fernández, José A.
Fernández-Valiñas, Antonio
Hernández, Daniel
Orozco, Joel
Lugo, Antonio
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-10
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Myasthenia gravis is an autoimmune disease characterized by muscle weakness.
Subjects with antibodies against acetylcholine usually have greater ocular symptoms, lower bulbar weakness, and fewer respiratory complications, compared to individuals with anti-MuSK antibodies.
The presence of positivity to both types of antibodies in the same patient is uncommon, and the clinical behavior of these individuals is uncertain.
A myasthenic crisis is characterized by respiratory and bulbar muscle weakness, causing acute respiratory failure which requires mechanical ventilatory support.
We present the case of a 73-year-old man with a medical history of myasthenia gravis and positive antibody titers against acetylcholine and anti-MuSK, who sought for medical assessment because of respiratory tract infection symptoms, dysphagia, and generalized weakness.
Initially, no respiratory distress was found.
After 24 hours the patient showed respiratory deterioration and neurological impairment.
Endotracheal intubation was rejected, so ventilatory support with noninvasive ventilation was started.
The patient was supported by intense respiratory therapy, and infusion of immunoglobulin was initiated.
The individual responded favorably, improving his general condition.
Weaning from noninvasive mechanical ventilation was possible after six days.
Our case illustrates that noninvasive ventilation, properly supported by intense respiratory therapy, can be a great option to avoid intubation in the myasthenic patient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fernández, José A.& Fernández-Valiñas, Antonio& Hernández, Daniel& Orozco, Joel& Lugo, Antonio. 2015. Myasthenic Crisis in an Elderly Patient with Positive Antibodies against Acetylcholine and Anti-MuSK, Successfully Treated with Noninvasive Mechanical Ventilation. Case Reports in Critical Care،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058207
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fernández, José A.…[et al.]. Myasthenic Crisis in an Elderly Patient with Positive Antibodies against Acetylcholine and Anti-MuSK, Successfully Treated with Noninvasive Mechanical Ventilation. Case Reports in Critical Care No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058207
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fernández, José A.& Fernández-Valiñas, Antonio& Hernández, Daniel& Orozco, Joel& Lugo, Antonio. Myasthenic Crisis in an Elderly Patient with Positive Antibodies against Acetylcholine and Anti-MuSK, Successfully Treated with Noninvasive Mechanical Ventilation. Case Reports in Critical Care. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058207
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058207
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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