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Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis
المؤلفون المشاركون
Taylor, Peter N.
Tabasum, Arshiya
Sanki, Gina
Burberry, David
Tennant, Brian P.
White, James
Okosieme, Onyebuchi
Aldridge, Andrew
Das, Gautam
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-05
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
An 82-year-old female with known hypothyroidism was admitted to hospital after being found on the floor.
On examination, she was unkempt, confused, bradycardic, hypothermic, and barely arousable.
Initial biochemistry revealed a thyroid stimulating hormone (TSH) of >100 mU/L and free thyroxine (FT4) level of 1.5 pmol/L which supported a diagnosis of myxoedema coma.
She was resuscitated and commenced on liothyronine, levothyroxine, and hydrocortisone and some improvement was made.
It became apparent that she was hiding and spitting out her oral levothyroxine including levothyroxine elixir.
Given the need for prompt alternative control, we sought advice from international experts where intramuscular levothyroxine was recommended.
She was managed from day 50 onwards with intramuscular levothyroxine 200 mcg once a week, which was subsequently increased to 500 mcg.
Thyroid function normalized and she made continual cognitive and physical progress and was discharged to a rehabilitation hospital.
Her intramuscular levothyroxine was stopped and she was subsequently restarted on oral levothyroxine, with a plan for on-going close monitoring of her thyroid function.
This report highlights the potential to use intramuscular levothyroxine in individuals with severe hypothyroidism arising from poor compliance with levothyroxine treatment or other potential causes such as impaired absorption.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Taylor, Peter N.& Tabasum, Arshiya& Sanki, Gina& Burberry, David& Tennant, Brian P.& White, James…[et al.]. 2015. Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058390
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Taylor, Peter N.…[et al.]. Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis. Case Reports in Endocrinology No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058390
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Taylor, Peter N.& Tabasum, Arshiya& Sanki, Gina& Burberry, David& Tennant, Brian P.& White, James…[et al.]. Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058390
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058390
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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