Successful Treatment of Multifocal Histiocytic Sarcoma Occurring after Renal Transplantation with Cladribine, High-Dose Cytarabine, G-CSF, and Mitoxantrone (CLAG-M) Followed by Allogeneic Hematopoietic Stem Cell Transplantation
المؤلفون المشاركون
Tomlin, Julia
Orosco, Ryan K.
Boles, Sarah
Tipps, Ann
Wang, Huan-You
Husseman, Jacob
Wieduwilt, Matthew
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Histiocytic sarcoma (HS) is a rare, aggressive malignancy.
Lesions previously called HS were typically non-Hodgkin lymphomas, not HS.
As such, chemotherapy directed at lymphoid neoplasms was frequently successful, but it is unclear if these regimens are ideal for HS.
We present a 33-year-old African gentleman who underwent sequential renal transplants for glomerulonephritis.
He subsequently developed HS of the upper airway and multiple cutaneous sites.
The patient received cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) followed by salvage ifosfamide, carboplatin, and etoposide (ICE) but had continuous progression of cutaneous involvement.
Cladribine, high-dose cytarabine, G-CSF, and mitoxantrone (CLAG-M) yielded a partial response with near resolution of disease.
Ultimately, the patient achieved a complete remission after myeloablative allogeneic hematopoietic stem cell transplant.
HS occurring after solid organ transplant raises the possibility of HS as a potential posttransplant malignancy.
The use of CLAG-M has not been reported in HS.
In this case, histiocyte-directed chemotherapy with CLAG-M was superior to lymphoma-directed regimens.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tomlin, Julia& Orosco, Ryan K.& Boles, Sarah& Tipps, Ann& Wang, Huan-You& Husseman, Jacob…[et al.]. 2015. Successful Treatment of Multifocal Histiocytic Sarcoma Occurring after Renal Transplantation with Cladribine, High-Dose Cytarabine, G-CSF, and Mitoxantrone (CLAG-M) Followed by Allogeneic Hematopoietic Stem Cell Transplantation. Case Reports in Hematology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1058633
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tomlin, Julia…[et al.]. Successful Treatment of Multifocal Histiocytic Sarcoma Occurring after Renal Transplantation with Cladribine, High-Dose Cytarabine, G-CSF, and Mitoxantrone (CLAG-M) Followed by Allogeneic Hematopoietic Stem Cell Transplantation. Case Reports in Hematology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1058633
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tomlin, Julia& Orosco, Ryan K.& Boles, Sarah& Tipps, Ann& Wang, Huan-You& Husseman, Jacob…[et al.]. Successful Treatment of Multifocal Histiocytic Sarcoma Occurring after Renal Transplantation with Cladribine, High-Dose Cytarabine, G-CSF, and Mitoxantrone (CLAG-M) Followed by Allogeneic Hematopoietic Stem Cell Transplantation. Case Reports in Hematology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1058633
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058633
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر