![](/images/graphics-bg.png)
Diffuse Large B Cell Lymphoma with Extensive Cutaneous Relapse
المؤلفون المشاركون
Malkan, Umit Yavuz
Yayar, Okan
Gunes, Gursel
Demiroglu, Haluk
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-20
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Herein, we aimed to report a diffuse large B cell lymphoma (DLBCL) case that had extensive cutaneous relapse with no skin involvement previously.
A 59-year-old man presented to hospital in April 2014 with fatigue, anorexia, fever, and anemia.
Cervical lymph node biopsy revealed CD20+, BCL2+, MUM1+, BCL6+ high grade B lymphoproliferative neoplasm.
After FISH investigation, he was diagnosed as DLBCL.
He was given 7 cycles of R-CHOP and achieved remission.
However, in November 2014, he had emerging skin lesions that cover nearly all of his body.
A control PET-CT revealed diffuse cutaneous involvement.
CD20+, BCL2+, MUM1+, BCL6+ high grade B cell lymphoma infiltration was detected with skin biopsy.
He was diagnosed as relapse lymphoma, so 2 cycles of R-DHAP were given.
There was no treatment response; therefore, R-ICE regimen was started.
The patient had achieved second complete remission and his skin lesions were completely regressed.
The involvement of skin with CD20+ cells after 7 cycles of rituximab therapy favors that there is a rituximab resistant disease which tends to involve the skin.
To conclude, DLBCL may relapse extensively with cutaneous involvement and the best treatment option in these patients is salvage chemotherapy followed by autologous peripheral blood stem cell transplantation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Malkan, Umit Yavuz& Gunes, Gursel& Yayar, Okan& Demiroglu, Haluk. 2015. Diffuse Large B Cell Lymphoma with Extensive Cutaneous Relapse. Case Reports in Medicine،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058779
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Malkan, Umit Yavuz…[et al.]. Diffuse Large B Cell Lymphoma with Extensive Cutaneous Relapse. Case Reports in Medicine No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058779
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Malkan, Umit Yavuz& Gunes, Gursel& Yayar, Okan& Demiroglu, Haluk. Diffuse Large B Cell Lymphoma with Extensive Cutaneous Relapse. Case Reports in Medicine. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058779
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058779
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)