Unusual Paraneoplastic Presentation of Cholangiocarcinoma
المؤلفون المشاركون
Opneja, Aman
Mahajan, Sonia
Kapoor, Sargam
Marur, Shanthi
Yang, Steve Hoseong
Manno, Rebecca
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-01
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Introduction.
Cutaneous paraneoplastic syndromes are a heterogeneous group of skin manifestations that occur in relation to many known malignancies.
Paraneoplastic occurrence of SCLE has been noted but is not commonly reported.
SCLE association with cholangiocarcinoma is rare.
Case Presentation.
A 72-year-old man with a history of extrahepatic stage IV cholangiocarcinoma presented with a pruritic rash.
Cholangiocarcinoma had been diagnosed three years earlier and was treated.
Five months after interruption of his chemotherapy due to a semiurgent surgery, he presented with explosive onset of a new pruritic rash, arthralgias, and lower extremity edema.
Physical exam revealed a scaly erythematous rash on his arms, hands, face, neck, legs, and trunk.
It was thick and scaly on sun exposed areas.
Skin biopsy revealed vacuolar interface dermatitis.
Immunofluorescence revealed IgM positive cytoid bodies scattered along the epidermal basement membrane zone.
PET-CT scanning revealed metabolically active recurrent disease in peripancreatic and periportal region with hypermetabolic lymph nodes.
Oral steroids and new regimen of chemotherapy were started.
Rash improved and steroids were tapered off.
Discussion.
Paraneoplastic syndromes demonstrate the complex interaction between the immune system and cancer.
Treatment resistant SCLE should raise a suspicion for paraneoplastic etiology.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Opneja, Aman& Mahajan, Sonia& Kapoor, Sargam& Marur, Shanthi& Yang, Steve Hoseong& Manno, Rebecca. 2015. Unusual Paraneoplastic Presentation of Cholangiocarcinoma. Case Reports in Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058912
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Opneja, Aman…[et al.]. Unusual Paraneoplastic Presentation of Cholangiocarcinoma. Case Reports in Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058912
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Opneja, Aman& Mahajan, Sonia& Kapoor, Sargam& Marur, Shanthi& Yang, Steve Hoseong& Manno, Rebecca. Unusual Paraneoplastic Presentation of Cholangiocarcinoma. Case Reports in Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058912
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058912
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر