Posterior Reversible Encephalopathy Syndrome as Presenting Form of Very Early Systemic Sclerosis
المؤلفون المشاركون
Pedraza, María Isabel
Barbado, Julia
Ruiz, Marina
Guerrero, Ángel Luis
المصدر
Case Reports in Neurological Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-23
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Introduction.
Posterior Reversible Encephalopathy Syndrome (PRES) is an increasingly recognized clinical and radiological entity with a wide spectrum of symptoms.
Its mechanism depends on failure of the blood-brain barrier due to high systemic blood pressure (BP) and loss of integrity of vascular endothelium related with different triggers.
Methods.
We aim to report a case of PRES induced by arterial hypertension and very early systemic sclerosis (SSc) not previously known.
Results.
A 64-year-old female was admitted due to 1-week pulsating headache more prominent on frontal scalp, accompanied by phonophobia, photophobia, and facial flushing.
Neurological exam revealed brisk deep tendon reflex.
Brain magnetic resonance imaging (MRI) showed subcortical lesions mainly located in posterior regions.
BP was monitored and episodic arterial hypertension was detected.
In laboratory tests positive anti-topoisomerase I antibodies were detected.
BP was controlled with angiotensin-converting-enzyme inhibitors and headache improved.
In a new MRI a month later improvement of white matter lesions was observed.
Capillaroscopy showed “active pattern,” considered typical of SSc.
Conclusion.
In SSc anti-endothelial cell antibodies impair vascular endothelium and liberation of vasoconstrictors leads to BP increasing and disruption of blood-brain barrier autoregulation mechanisms.
PRES can be the first manifestation of very early SSc and this entity should be considered even in absence of skin lesions or Raynaud phenomenon.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pedraza, María Isabel& Barbado, Julia& Ruiz, Marina& Guerrero, Ángel Luis. 2015. Posterior Reversible Encephalopathy Syndrome as Presenting Form of Very Early Systemic Sclerosis. Case Reports in Neurological Medicine،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1059009
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pedraza, María Isabel…[et al.]. Posterior Reversible Encephalopathy Syndrome as Presenting Form of Very Early Systemic Sclerosis. Case Reports in Neurological Medicine No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1059009
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pedraza, María Isabel& Barbado, Julia& Ruiz, Marina& Guerrero, Ángel Luis. Posterior Reversible Encephalopathy Syndrome as Presenting Form of Very Early Systemic Sclerosis. Case Reports in Neurological Medicine. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1059009
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1059009
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر