Effective Downsizing of a Large Oesophageal Gastrointestinal Stromal Tumour with Neoadjuvant Imatinib Enabling an Uncomplicated and without Tumour Rupture Laparoscopic-Assisted Ivor-Lewis Oesophagectomy
المؤلفون المشاركون
Mudan, Satvinder
Costa Neves, Mafalda
Giakoustidis, Alexandros
Benson, Charlotte
Kyriakos, Neofytou
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Neoadjuvant imatinib for gastrointestinal stromal tumours (GISTs) is increasingly used nowadays.
As oesophagectomy is associated with high morbidity and mortality, a preoperative downsizing of an oesophageal GIST to limit the extent of resection would be ideal.
Because these tumours are rare and neoadjuvant treatment with imatinib is recent, there is limited literature available regarding neoadjuvant administration of imatinib in patients with oesophageal GISTs.
A 50-year-old woman presented with total dysphagia.
An upper endoscopy and biopsy revealed a large submucosal KIT-positive GIST obstructing the mid oesophagus.
CT confirmed a lesion measuring 99 mm × 50 mm × 104 mm.
Because the size and location of the tumour increased the risk of intraoperative rupture, it was decided to administer preoperative imatinib.
The patient had an excellent clinical and radiological response.
Her dysphagia gradually resolved and the follow-up CT scans of the first 10 months showed a gradually reducing tumour size to 54 mm × 33 mm × 42 mm.
The patient underwent an uneventful laparoscopic-assisted Ivor-Lewis oesophagectomy.
Postoperatively, the patient continued with adjuvant imatinib.
At the last follow-up, 1 year from operation and 38 months from the diagnosis, the patient is disease free.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kyriakos, Neofytou& Costa Neves, Mafalda& Giakoustidis, Alexandros& Benson, Charlotte& Mudan, Satvinder. 2015. Effective Downsizing of a Large Oesophageal Gastrointestinal Stromal Tumour with Neoadjuvant Imatinib Enabling an Uncomplicated and without Tumour Rupture Laparoscopic-Assisted Ivor-Lewis Oesophagectomy. Case Reports in Oncological Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1059244
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kyriakos, Neofytou…[et al.]. Effective Downsizing of a Large Oesophageal Gastrointestinal Stromal Tumour with Neoadjuvant Imatinib Enabling an Uncomplicated and without Tumour Rupture Laparoscopic-Assisted Ivor-Lewis Oesophagectomy. Case Reports in Oncological Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1059244
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kyriakos, Neofytou& Costa Neves, Mafalda& Giakoustidis, Alexandros& Benson, Charlotte& Mudan, Satvinder. Effective Downsizing of a Large Oesophageal Gastrointestinal Stromal Tumour with Neoadjuvant Imatinib Enabling an Uncomplicated and without Tumour Rupture Laparoscopic-Assisted Ivor-Lewis Oesophagectomy. Case Reports in Oncological Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1059244
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1059244
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر