Morbid Obesity as Early Manifestation of Occult Hypothalamic-Pituitary LCH with Delay in Treatment
المؤلفون المشاركون
Keates-Baleeiro, Jennifer
Rincon, Marielisa
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-30
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Morbid obesity presents unique challenges in managing additional disease processes.
A 16-year-old male with a history of central diabetes insipidus (DI) and hypothyroidism developed destructive lesions in both his right mandible and brain, which were not discovered until the patient presented for tinnitus, 8 years after his initial diagnosis with DI.
Langerhans cell histiocytosis (LCH) was diagnosed on pathologic biopsy.
The patient’s initial body mass index (BMI) was 54.5 kg/m2 so a unique treatment approach with single agent cladribine (2-CdA) was offered as traditional steroid therapy could worsen his endocrine dysfunction.
The patient presented with neurodegenerative sequelae from the central LCH, possibly due to a delay in diagnosis and therapy.
This case highlights difficulties in managing obese patients in an oncology setting and provides an illustrative case of how obesity may mask other comorbid conditions.
Close supervision of complex obese patients with coordinated endocrinology and oncology care is vital.
For the primary care practitioner, monitoring abrupt changes in BMI with serial cranial imaging may lead to a prompt diagnosis and prevention of further neurodegenerative effects.
The use of 2-CdA was found to successfully bring the patient’s LCH into remission without the additional risks of steroid therapy in a morbidly obese patient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Keates-Baleeiro, Jennifer& Rincon, Marielisa. 2015. Morbid Obesity as Early Manifestation of Occult Hypothalamic-Pituitary LCH with Delay in Treatment. Case Reports in Oncological Medicine،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1059328
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Keates-Baleeiro, Jennifer& Rincon, Marielisa. Morbid Obesity as Early Manifestation of Occult Hypothalamic-Pituitary LCH with Delay in Treatment. Case Reports in Oncological Medicine No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1059328
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Keates-Baleeiro, Jennifer& Rincon, Marielisa. Morbid Obesity as Early Manifestation of Occult Hypothalamic-Pituitary LCH with Delay in Treatment. Case Reports in Oncological Medicine. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1059328
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1059328
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر