Anti-NMDA Receptor Encephalitis in a Patient with Previous Psychosis and Neurological Abnormalities: A Diagnostic Challenge

المؤلفون المشاركون

Heekin, R. David
Catalano, Maria C.
Frontera, Alfred T.
Catalano, Glenn

المصدر

Case Reports in Psychiatry

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-4، 4ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-06-14

دولة النشر

مصر

عدد الصفحات

4

التخصصات الرئيسية

علم النفس
الطب البشري
الطب النفسي

الملخص EN

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder characterized by IgG autoantibodies directed against the NR1 subunit of the NMDA glutamate receptor.

Psychiatric symptoms are common and include psychosis, mania, depressed mood, aggression, and speech abnormalities.

Neurological symptoms such as seizures, decreased responsiveness, dyskinesias, and other movement abnormalities and/or autonomic instability are frequently seen as well.

We present the case of a woman who was followed up at our facility for over 14 years for the treatment of multiple neuropsychiatric symptoms.

Initially, she presented with paresthesias, memory loss, and manic symptoms.

Nine years later, she presented to our facility again, this time with left sided numbness, left eyelid droop, and word finding difficulties.

Finally, five years later, she presented with manic symptoms, hallucinations, and memory impairment.

During her hospitalization, she subsequently developed catatonic symptoms and seizures.

During her stay, it was discovered that she was positive for anti-NMDA receptor antibodies and her symptoms responded well to appropriate therapy.

This case demonstrates that it may be useful for clinicians to consider screening for anti-NMDA receptor antibodies in long-term patients with neuropsychiatric symptoms that have not adequately responded to therapy.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Heekin, R. David& Catalano, Maria C.& Frontera, Alfred T.& Catalano, Glenn. 2015. Anti-NMDA Receptor Encephalitis in a Patient with Previous Psychosis and Neurological Abnormalities: A Diagnostic Challenge. Case Reports in Psychiatry،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059826

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Heekin, R. David…[et al.]. Anti-NMDA Receptor Encephalitis in a Patient with Previous Psychosis and Neurological Abnormalities: A Diagnostic Challenge. Case Reports in Psychiatry No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059826

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Heekin, R. David& Catalano, Maria C.& Frontera, Alfred T.& Catalano, Glenn. Anti-NMDA Receptor Encephalitis in a Patient with Previous Psychosis and Neurological Abnormalities: A Diagnostic Challenge. Case Reports in Psychiatry. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059826

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1059826