Beneficial Effects of Palmitoylethanolamide on Expressive Language, Cognition, and Behaviors in Autism: A Report of Two Cases
المؤلفون المشاركون
Antonucci, Nicola
Siniscalco, Dario
Cirillo, Alessandra
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
علم النفس
الطب البشري
الطب النفسي
الملخص EN
Introduction.
Autism spectrum disorders are defined by behavioral and language atypias.
Growing body of evidence indicates inflammatory mediators may contribute to the condition.
Palmitoylethanolamide (PEA) is naturally occurring and has been available as a nonprescription medical food supplement in Europe since 2008.
PEA has been tested in thousands of human subjects without any noted significant side effects.
Here we report the first cases of the administration of PEA to two children with autism.
Case Presentations.
The first 13-year-old male child (Subject 1) presented with a total IgE of 572 IU/mL (nl < 200) and with low mature CD57+ natural killer cell counts (32 cells/µL; nl = 60–300 cells/µL) and with significant eczema and allergic stigmata.
Expressive language, as measured by mean length of utterance, and overall autism severity as measured by the Childhood Autism Rating Scale, Second Edition, improved significantly.
Atopic symptoms diminished.
No side effects were reported.
The second male child, age 15 (Subject 2), also displayed noticeable and rapid improvements in cognitive, behaviors, and sociability.
Conclusion.
Currently, there is no definitive treatment for autism condition.
Palmitoylethanolamide could be an effective treatment for autism syndrome.
We propose appropriate double-blind clinical trials to further explore palmitoylethanolamide efficacy and safety.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Antonucci, Nicola& Cirillo, Alessandra& Siniscalco, Dario. 2015. Beneficial Effects of Palmitoylethanolamide on Expressive Language, Cognition, and Behaviors in Autism: A Report of Two Cases. Case Reports in Psychiatry،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1059829
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Antonucci, Nicola…[et al.]. Beneficial Effects of Palmitoylethanolamide on Expressive Language, Cognition, and Behaviors in Autism: A Report of Two Cases. Case Reports in Psychiatry No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1059829
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Antonucci, Nicola& Cirillo, Alessandra& Siniscalco, Dario. Beneficial Effects of Palmitoylethanolamide on Expressive Language, Cognition, and Behaviors in Autism: A Report of Two Cases. Case Reports in Psychiatry. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1059829
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1059829
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر